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Thesis topic proposal
 
Investigating the protective role of Hsp27 in cardio- and cerebrovascular dysfunctions in transgenic mouse models

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: Erzsébet Melinda Tóth
Location of studies (in Hungarian): BRC Institute of Biochemistry
Abbreviation of location of studies: SzBK


Description of the research topic:

Heat shock proteins (Hsps) are evolutionarily conserved chaperone proteins which are upregulated under different stress conditions and in various diseases, therefore they are promising therapeutic targets. In the current project our aim is to study the protective role of the small Hsp, Hsp27, especially focusing on cardio- and cerebrovascular dysfunctions, using our Hsp27 overexpressing transgenic mice and different disease model strains (a model of hyperlipidemia and a model of Alzheimer’s disease).

Required language skills: English
Number of students who can be accepted: 1

Deadline for application: 2020-12-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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