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Thesis topic proposal
 
Tibor Pankotai
Mapping the connection between DNA repair and tumorigenesis

THESIS TOPIC PROPOSAL

Institute: University of Szeged
theoretical medicine
Doctoral School of Interdisciplinary Medicine

Thesis supervisor: Tibor Pankotai
Location of studies (in Hungarian): University of Szeged Faculty of Dentistry
Abbreviation of location of studies: FOKOR


Description of the research topic:

Faithful repair of DNA damages is indispensable, since improper repair process can lead to genome instability, chromosomal translocations and cancer formation. Cells have developed several pathways eligible for DNA repair and the choice as well as the balance among them must be tightly regulated to preserve genome integrity. For the better understanding of these mechanisms, detection and qualification of tumors are essential to recognize cancer development even at early stages. The project has significant implications in understanding DNA repair-related mechanisms revealing specific mechanisms susceptible for genome instability and in helping us to understand why certain mutations and translocations are recurrent in several cancer types.

Required language skills: english
Number of students who can be accepted: 1

Deadline for application: 2020-12-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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