ODT - THESIS TOPIC: György Trencsényi: The role of radiolabeled ...


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Thesis topic proposal

The role of radiolabeled cyclodextrins in in vivo PET imaging of experimental tumor metastases.

THESIS TOPIC PROPOSAL

Institute: University of Debrecen
clinical medicine
Gyula Petrányi Doctoral School of Allergy and Clinical Immunology

Thesis supervisor: György Trencsényi
Location of studies (in Hungarian): DE, ÁOK, Orvosi Képalkotó Intézet, Nukleáris Medicina Nem Önálló Tanszék
Abbreviation of location of studies: NMT

Description of the research topic:

Cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) plays an important role in the development of tumor metastases. PGE-2 is the basis of many antitumor therapies and can be a useful target in the diagnosis of metastases by positron emission tomography (PET) imaging. The aim of the work is to synthesize PGE2-specific Gallium-68 (68Ga)-labeled cyclodextrins, investigate their tumor-targeting properties and in vivo biodistribution.

Required language skills: angol középfok
Recommended language skills (in Hungarian): angol középfok
Further requirements:
molekuláris biológus, orvos végzettség

Number of students who can be accepted: 1

Deadline for application: 2020-08-30

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).