ODT - THESIS TOPIC: Gergő Szanda: Interactions between intracellular signalling ...


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Thesis topic proposal

Interactions between intracellular signalling pathways regulating energy metabolism

THESIS TOPIC PROPOSAL

Institute: Semmelweis University, Budapest
theoretical medicine
Doctoral School of Molecular Medicine

Thesis supervisor: Gergő Szanda
Location of studies (in Hungarian): Semmelweis Egyetem Élettani Intézet
Abbreviation of location of studies: SE

Description of the research topic:

We seek to reveal the intracellular interaction pathways between the signal transduction of the hormonal (e.g. ghrelin, leptin, insulin), paracrine and neurotransmitter stimuli (dopamine, endocannabinoids) of hypothalamic neurons regulating energy metabolism and food-intake. To this end, we apply cell culture, molecular biological, protein detection and microscopic as well as energy transfer (FRET, BRET) techniques and intend to extend our studies to animal models as well. By studying the interplay of such signal transduction pathways we may identify pivotal points in the regulation of energy metabolism under physiological and pathophysiological (e.g. obesity) conditions.

Number of students who can be accepted: 1

Deadline for application: 2020-10-17

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).