Thesis supervisor: László Bodai
Location of studies (in Hungarian): University of Szeged, Faculty of Science and Informatics, Department of Biochemistry and Molecular Biology Abbreviation of location of studies: SZTE
Description of the research topic:
Several neurodegenerative disorders, like Alzheimer, Parkinson or Huntington disease are caused by structurally abnormal and/or misfolded proteins. These proteopathies are characterized by aggregation of abnormal proteins and multifaceted pathomechansims affecting several molecular processes, which are still not clearly elucidated. Our research goal is to investigate the molecular background of protein misfolding induced neurodegeneration, primarily focusing on proteopathy associated changes in the levels of non-coding RNAs (miRNAs and long non-coding RNAs) and their roles in proteopathy. We plan to use Drosophila models of Huntington disease in our experiments.
Required language skills: English Further requirements: Hands-on experience in methods of molecular biology and genetics. Capability of independent interpretation of scientific literature.
Number of students who can be accepted: 1
Deadline for application: 2020-09-25
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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