Thesis topic proposal
Tibor Páli
Biophysical and biochemical studies of yeast vacuolar membranes


Institute: University of Szeged
theoretical medicine
Doctoral School of Multidisciplinary Medical Scienses

Thesis supervisor: Tibor Páli
co-supervisor: Zoltán Kóta
Web address (URL): http://www.brc.mta.hu/biophys_membrane_biophysics.php
Location of studies (in Hungarian): Institute of Biophysics BRC, HAS
Abbreviation of location of studies: SZBK

Description of the research topic:

The project aims at gathering functionally relevant structural data in yeast vacuolar membranes on the ATP dependent proton pumping of V-ATPase using spectroscopic techniques. The dependence of both the ATP hydrolysis and proton pumping will be studied, primarily in native membranes, as a function of the physical state of the membrane, external conditions (temperature, oscillating electric field) and non-covalent V-ATPase inhibitors. These experiments will provide data for a better understanding of the functioning and regulation of the membrane-bound proton pumping molecular machinery, the V-ATPase.

Required language skills: English
Number of students who can be accepted: 1

Deadline for application: 2020-08-14

2020. X. 20.
ODT online ülés
Az ODT következő, online ülésére 2020. november 6-án 10.00 órakor kerül sor.

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