Thesis supervisor: Eszter Ari
co-supervisor: Máté Varga
Location of studies (in Hungarian): ELTE Abbreviation of location of studies: MTA
Description of the research topic:
In the past decade zebrafish has become a wildly popular and successful model organism of biomedical research. Despite its numerous advantages, in certain areas (e.g. studies related to behavioral neuroscience) the use of zebrafish is limited, therefore the use of other fish species could be advantageous. In order to apply the new generation of transgenic and genome editing tools to any model organism, however, we need a high quality genome sequence. The successful candidate will be involved in the ongoing, de novo assembly of the small genome of a labyrinth fish species. We are going to use a complex approach, where long and short sequencing reads from different genome sequencing strategies will be combined. Gene annotation will be performed using transcriptomic data and established ortholog-based approaches. Comparative analysis of the new genome with other, high quality fish genomes will be also performed.
Requirements: Basic programming skills in Python or R, basic knowledge of Linux commands, strong Genetics background. Some experience in genome and/or transcriptome-assembly pipelines is favored. Interested applicants are advised to send a CV (EuroPass format) and a motivation letter. Please also list two references who can be contacted regarding your application.
Required language skills: English Number of students who can be accepted: 1
Deadline for application: 2020-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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