ODT - THESIS TOPIC: Hajnalka Ábrahám: Study of the link ...


	Login Forum Organisation officers member institutions resolutions (in Hung.) by-laws (in Hung.) regulations Doctoral program doctoral schools by institution by research field by number ceased working academic staff member by name by research topic archives thesis topic proposals by doctoral school by research field by research topic supervision of PhD students search students Theses defended by institution by research field by name by date by doctoral school Naturalized degrees by institution by research field by name by date Habilitation presentations by institution by branch of science by name Documents (all in Hung.) public documents news legal backgrounds guidelines Contacts contact details partners

Thesis topic proposal

Study of the link between pharmaceutical fever and febrile seizure reduction and the prevention of the development of hippocampal sclerosis

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Neurosciences

Thesis supervisor: Hajnalka Ábrahám
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsies, and based on earlier data, more than 70% of the patients have hippocampal sclerosis (HS). Frequently, HS is preceded by childhood complex febrile seizure (FS). Our aim is to investigate the structural and functional changes caused by FS and NSAIDs used for the fever reduction. Our examinations will be performed on animal models of FS, on organotypic hippocampal and neocortical slice and cell culture. In addition to the experiments, surgically removed cortical tissue of TLE patients with HS and with a history of FS will be examined. Those results obtained in experiments will be tested in the surgical tissue of the patients.

Number of students who can be accepted: 1

Deadline for application: 2020-05-15

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).