Thesis topic proposal
Zsolt László Datki
In vivo modeling the role of serotonergic system in longevity regulation


Institute: University of Szeged
theoretical medicine
Theoretical Medicine Doctoral School

Thesis supervisor: Zsolt László Datki
Location of studies (in Hungarian): University of Szeged Faculty of Medicine Department of Psychiatry
Abbreviation of location of studies: PSYCH

Description of the research topic:

The aim of our research is to investigate the role of the serotonergic system in the aging process. The Bdelloid rotifers (Philodina acuticornis, Adineta vaga; phylum Rotifera) are well-known and validated in vivo aging models. These microscopic invertebrates have a complex nervous system mainly based on the serotonergic transmission; however, all other classic neurotransmitters are detectable in them. Based on our knowledge, there were no previous publications about the direct impact of serotonergic system on lifespan in academic literature; however, we have preliminary data supporting this relation. The correlation between the serotonergic system and longevity may have potential human relevance.

Required language skills: english
Number of students who can be accepted: 1

Deadline for application: 2019-12-31

2019. IX. 13.
ODT ülés
Az ODT következő ülésére 2019. november 22-én 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

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