Thesis topic proposal
Role of immunosuppressive microenvironment in development of malignant tumors


Institute: University of Szeged
theoretical medicine
Doctoral School of Multidisciplinary Medical Scienses

Thesis supervisor: László Krenács
Location of studies (in Hungarian): T-cell Medical Diagnostics Ltd, Laboratory of Tumor Pathology and Molecular Diagnost
Abbreviation of location of studies: DPL

Description of the research topic:

Aim of the research is to investigate immunological and immunogenetical factors that are able to provide immune priviledge for lymphoreticular and solid tumors. The study will incorporate immunological and molecular pathological analysis of peripheral T-cell lymphomas, Hodgkin lymphomas, melanomas, gliomas, and breast cancer cases. We are intended to explore the communication between tumor cells and tumoral microenvironment including tumoral stroma that can promote tumoral growth.

Methodology will be used during the research:
- Immunohistochemistry
- In situ hybridization
- Polymerase chain raection
- Molecular cloning
- Cell culture

Required language skills: English
Further requirements: 
TDK munka

Number of students who can be accepted: 1

Deadline for application: 2019-12-19

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