Thesis topic proposal
Attila Csikász-Nagy
Dynamical modelling of biological regulatory networks


Institute: Pázmány Péter Catholic University, Budapest
Roska Tamás Doctoral School of Sciences and Technology

Thesis supervisor: Attila Csikász-Nagy
Location of studies (in Hungarian): PPCU FIT Roska Tamás Doctoral School of Technology and Sciences
Abbreviation of location of studies: PPKE

Description of the research topic:

Individual cells can give diverse responses to inputs received from the environment. A complex molecular regulatory network controls the signal processing and response reactions of the cell. Such networks with feed-forward and feedback loops can show interesting dynamical behaviours, what we can investigate only computationally. We will investigate by mathematical modelling various biological regulatory networks. Model analysis will help us to gain a better understanding of the biological system and the models will also support us in designing further experiments for better understanding. We will investigate by mathematical and computational modelling the regulatory networks controlling cell division, cell growth, circadian rhythm and cell-cell interactions and how these systems are connected to each other.

Required language skills: English intermediate
Recommended language skills (in Hungarian): English advanced
Further requirements: 
mathematics knowledge: differential equations, biology knowldege: molecular biology, programming at least at basic level in at least one language, physical chamistry knowledge: reaction kinetics

Number of students who can be accepted: 1

Deadline for application: 2020-01-30

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