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Thesis topic proposal
 
Effect of hormonal changes in menopause on cognitive functions

THESIS TOPIC PROPOSAL

Institute: Budapest University of Technology and Economics
psychology
Doctoral School of Psychology (Cognitive Science)

Thesis supervisor: Zsófia Anna Gaál
Location of studies (in Hungarian): MTA TTK, Kognitív Idegtudományi és Pszichofiziológiai Intézet
Abbreviation of location of studies: MTA


Description of the research topic:

Animal experiments show that female sex hormones have a significant effect on brain structure and function, and hence on cognitive function as well. High oestrogen level, for example, improves performance in hippocampus-sensitive tasks, while deteriorates performance in striatum-sensitive tasks. In our experiments we study how human cognitive functions change with hormonal changes and how this is influenced by hormone therapy after menopause. We study cognitive functions with psychological tests and event-related potentials, and the changes in brain functional connectivity is analysed by the EEG.

Korol, D.L., Pisani, S.L. (2015) Estrogens and cognition: Friends or foes? An evaluation of the opposing effects of estrogens on learning and memory. Hormones and Behavior, 74, 105-115.
Rocca, W. A., Grossardt, B. R., & Shuster, L. T. (2011). Oophorectomy, menopause, estrogen treatment, and cognitive aging: Clinical evidence for a window of opportunity. Brain Research, 1379, 188–198.
Morgan, K. N., Derby, C. A., & Gleason, C. E. (2018). Cognitive Changes with Reproductive Aging, Perimenopause, and Menopause. Obstetrics and Gynecology Clinics of North America, 45(4), 751–763.

Required language skills: english
Number of students who can be accepted: 1

Deadline for application: 2019-05-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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