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Thesis topic proposal
 
Genetic abnormalities in plasma cell myeloma

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Medicine

Thesis supervisor: Donát Alpár
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK


Description of the research topic:

Myeloma is a genetically and clinically heterogeneous, incurable malignancy occurring through the clonal proliferation of terminally differentiated B-cells. The various disease-associated, recurrent genetic aberrations and their combinations allow the determination of biologically and clinically relevant subgroups. In this study, we aim to investigate (i) the evolution of biologically and/or prognostically important cytogenetic aberrations in plasma cell myeloma; (ii) the applicability of various cytogenetic and molecular genetic techniques in the pathological diagnostics of myeloma, and (iii) the correlation between clinical features and genetic alterations detectable using novel methods with potential utilization in diagnostics.

Number of students who can be accepted: 1

Deadline for application: 2019-05-17


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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