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Thesis topic proposal
 
István Ilisz
Physico-chemical characterization and evaluation of chiral recognition on a chromatographic base

THESIS TOPIC PROPOSAL

Institute: University of Szeged
pharmaceutics
Doctoral School of Pharmaceutical Sciences

Thesis supervisor: István Ilisz
Location of studies (in Hungarian): Szeged
Abbreviation of location of studies: SZTE


Description of the research topic:

Chirality, the most important form of molecular asymmetry, is universal and chirality on molecular level plays an essential role in biological systems. That is the reason why pharmaceutical industry pays outstanding attention to chiral compounds when developing biologically active chiral pharmacons. By investigating the chromatographic properties of various model compounds we aim to elucidate the effects of the applied conditions on the separation ability and enantioselectivity of various chiral stationary phases. Our main goal is to reveal relationships between the molecular structure and the acquired chromatographic properties. The investigated potential drug candidates have diverse biological and chemical properties, however, the structural similarities and the applied chiral stationary phases can serve as a basis to reach a deeper understanding of the structure-retention (selectivity) relationships.

Number of students who can be accepted: 1

Deadline for application: 2019-06-17


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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