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Thesis topic proposal
 
Szilvia Fiatal
Investigating genetic susceptibility to cardiovascular risk factors using genetic epidemiology methods.

THESIS TOPIC PROPOSAL

Institute: University of Debrecen
general health sciences
Doctoral School of Health Sciences

Thesis supervisor: Szilvia Fiatal
Location of studies (in Hungarian): Department of Preventive Medicine, Faculty of Public Health, University of Debrecen, Hungary
Abbreviation of location of studies: UDFPH


Description of the research topic:

There is now compelling evidence that a complex interplay between genetic determinants and environmental factors is behind the cardiovascular disease susceptibility. This research seeks to describe genetic background of selected cardiovascular risk factors by estimating the frequency and distribution pattern of single nucleotide polymorphisms (SNPs) in genes coding proteins involved in the regulation of blood pressure, metabolic pathways related to lipid and glucose metabolisms and also in that of affecting health behavior resulting in unhealthy lifestyle (smoking, alcohol-dependence, low physical activity, nutritional problems) in the Hungarian general and Roma populations. The further aim is to develop predictive models (microarray platforms) feasible for individual- and population-level risk assessment by using SNPs that significantly increase cardiovascular susceptibility and having high predictive value. The developed models can be used in identification of individuals and groups at high risk of being susceptible to cardiovascular diseases.

Required language skills: English
Further requirements: 
Social skills and competences:organizational skills, Computer skills and competences :experience in statistical analyses: excellent command of Microsoft Office TM, excellent command of data management and analysis applications

Number of students who can be accepted: 1

Deadline for application: 2018-05-15


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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