Thesis supervisor: Katalin Schlett
Location of studies (in Hungarian): Eötvös Loránd University, Dept. Physiology and Neurobiology, Neuronal Cell Biology Research Group Abbreviation of location of studies: ELTE
Description of the research topic:
The project aims to elucidate novel molecular pathways regulating neuronal plasticity, concentrating primarily on the role of a novel serine –threonine kinase, protein kinase D (PKD) in neurons. Experiments are carried out in embryonic hippocampal cell cultures or in acute brain slices. When relevant, we have experience with validating molecular findings with behavioral or learning tests carried out in transgenic mouse lines. Our major interests are focused on synapse formation, maturation and maintenance, including the regulation of actin polymerization within dendritic spines (see Bencsik et al., J. Cell Biol., 2015) or the traffic and turnover of neurotransmitter receptors (see Sziber et al., Mol. Biol. Cell, 2017). Besides using standard molecular biological methods, we are keen on applying fluorescent live cell imaging and quantitative microscopy, optogenetics and electrophysiology in cultivated neurons. The successful candidate must speak fluent English and should have experience with mammalian cell culture and animal handling.
Required language skills: fluent English (at least B2) Further requirements: MSc thesis in neuroscience, cell biology or molecular biology; previous experience with mammalian cell culture and animal handling is an advantage
Number of students who can be accepted: 1
Deadline for application: 2018-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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