Thesis supervisor: Zsuzsanna Hamari
Location of studies (in Hungarian): University of Szeged, Faculty of Sciences, Department of Microbiology Abbreviation of location of studies: SzTE
Description of the research topic:
The High Mobility Group –box (HMGB) proteins are non-histone chromatin associated proteins, which promote the stabile binding of chromatin remodeling complexes and other chromatin associated factors to the chromatin due to their ability to bind the DNA and establish interactions with the chromatin modulating factors. We had identified three HMGB proteins in Aspergillus nidulans, HmbA, HmbB and HmbC. We had described the physiological role of one of these proteins, HmbB (Karácsony és mtsai 2014, 2015). We aim to shed light on the physiological role of HmbA and HmbC.
Karácsony Z, Gácser A, Vágvölgyi C, Scazzocchio C, Hamari Z. (2014) A dually located multi-HMG-box protein of Aspergillus nidulans has a crucial role in conidial and ascospore germination. Mol Microbiol. 2014 Oct;94(2):383-402.
Karácsony Z, Gácser A, Vágvölgyi C, Hamari Z. (2015) Further characterisation of the role of the mitochondrial HMG-Box protein in the intracellular redox environment of Aspergillus nidulans. Microbiology. 2015 Oct;161(10):1897-908
Required language skills: English B2 Further requirements: basic microbiological and molecular biological skills
Number of students who can be accepted: 1
Deadline for application: 2018-09-26
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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