Thesis supervisor: Ildikó Unk
Location of studies (in Hungarian): Institute of Genetics, Biological Research Centre of the Hungarian Academy of Sciences Abbreviation of location of studies: SZBK
Description of the research topic:
Our research focuses on the regulation of DNA damage bypass mechanisms using the model organism baker yeast, Saccharomyces cerevisiae. We search for proteins regulating damage bypass using different methods. Recently we identified the Def1 protein as an essential factor for induced mutagenesis. We showed that Def1 regulates the access of lesion bypass polymerases to the replication fork. We also discovered a new mechanism through which Def1 affects the accessibility of the replication fork. We are currently pursuing experiments to unravel the details of this new mechanism and to map the interacting partners of Def1.
Required language skills: English B2 Further requirements: experience in the basic methods of molecular biology
Number of students who can be accepted: 2
Deadline for application: 2018-09-26
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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