Login
 Forum
 
 
Thesis topic proposal
 
László Magor Lőrincz
Role of identified serotonergic and GABAergic neurons in brain state dependent activity

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: László Magor Lőrincz
Location of studies (in Hungarian): University of Szeged, Department of Physiology, Anatomy and Neuroscience, Szeged, Közép fasor 52.
Abbreviation of location of studies: SzTE


Description of the research topic:

Serotonin is a major neuromodulator involved in various physiological and pathological functions. We have previously shown that selective activation of serotonergic neurons leads to prominent and fast suppression of cortical activity. In this project the role of various identified dorsal raphé nurons (serotonergic and GABAergic) will be tested by using optical imaging of genetically encoded calcium indicators in awake behaving mice. For testing causality the activity of serotonergic and GABAergic neurons will be selectively and bidirectionally modulated and their effects on brain states quantified. These results could shed new light on the mechanisms of serotonergic neuromodulation.

Required language skills: English B2
Further requirements: 
minimum good PC user skills, science diploma, excellent problem solving skills

Number of students who can be accepted: 1

Deadline for application: 2018-09-26


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )