Thesis supervisor: Lajos Haracska
Location of studies (in Hungarian): Institute of Genetics, Biological Research Centre of the Hungarian Academy of Sciences Abbreviation of location of studies: SZBK
Description of the research topic:
In cells, DNA is damaged by several endogenous and exogenous factors. If the damage is not repaired, the replication machinery stalls during DNA doubling. Different mechanisms have evolved to rescue stalled replication forks; these help replication proceed over damaged DNA in an error-free or error-prone way. Error-prone processes, which cause mutations, increase the risk of carcinogenesis, while error-free replication protects genome stability and thus fulfils a tumour suppressor function.
Our research group investigates the causes and mechanisms of mutagenesis and carcinogenesis and strives to answer the questions of what the common roots of evolution and carcinogenesis are and how point mutations and chromosome rearrangements are generated.
Required language skills: English B2 Further requirements: A grade average above 4.0, participation at TDK or other competititons, lab experience.
Number of students who can be accepted: 1
Deadline for application: 2018-09-26
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
Login
