Thesis supervisor: Balázs Papp
co-supervisor: Balázs Szappanos
Location of studies (in Hungarian): Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences Abbreviation of location of studies: SZBK
Description of the research topic:
Understanding the patterns and causes of diversity in molecular phenotypes is a central challenge of evolutionary biology. The metabolome (i.e. the collection of metabolite concentrations) is a key molecular phenotype that lies between gene expression and physiological traits. Although gene expression evolution has been extensively studied in the field of molecular evolution, its links to metabolome divergence remains largely unexplored. Recent availability of comparative metabolomics and transcriptomic datasets across multiple species allows us, for the first time, to address this issue. More generally, studying the links between metabolome and gene expression evolution will provide new insights into the evolutionary forces shaping the different layers of molecular phenotypes and further our understanding of the relationship between gene expression and metabolic traits, including disease states.
Required language skills: English B2 Recommended language skills (in Hungarian): English Further requirements: programming skills and experience in bioinformatics
Number of students who can be accepted: 1
Deadline for application: 2018-09-26
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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