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Thesis topic proposal
 
László Norbert Galgóczi
Attila Borics
Investigation of the structure and molecular interactions of cystein-rich antifungal proteins

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: Attila Borics
co-supervisor: László Norbert Galgóczi
Location of studies (in Hungarian): Institutes of Biochemistry and Plant Biology, BRC-HAS
Abbreviation of location of studies: SZBK


Description of the research topic:

Small, cysteine-rich, plant defensin-like antifungal proteins expressed by ascomycetes constitute a feasible basis for the development of novel antifungal molecules. Therefore, deep understanding of structure-activity relationships of such proteins are of high importance. Our investigations include isolation of wild-type proteins, their homologous and heterologous expression, in vitro testing for antifungal activity and the investigation of three dimensional molecular structure utilizing experimental (ECD, NMR) and in silico methods.

Recommended language skills (in Hungarian): English B2
Further requirements: 
Basic microbiology background, strong backround and interest in molecular and structural biology, laboratory work experience, user-level informatics skills.

Number of students who can be accepted: 1

Deadline for application: 2018-09-26


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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