Thesis supervisor: László Nagy
Location of studies (in Hungarian): University of Debrecen Abbreviation of location of studies: DEÁOK
Description of the research topic:
The proposed research is the logical continuation of the work described in our publication (Daniel et al 2014). We are proposing to systematically analyze the interaction of key transcriptional regulators of macrophage polarization and angiogenic activity. We propose two specific aims. In aim 1 we will use state of the art epigenomic methods to map the contribution and genome-wide interaction, enhancer selection of a set of transcription factors (PPARg, STAT6, EGR2). In the second aim we will study the regulation of twokey angiogenic genes VEGFa and HBEGF to understand how macrophage polarization and gene expression leads to an angiogenic phenotype of the cell.
Number of students who can be accepted: 1
Deadline for application: 2018-05-15
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
Login
