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Thesis topic proposal
 
Veronika Halas
Evaluation of Fumonizin B1 exposure through structural and functional changes in the gut

THESIS TOPIC PROPOSAL

Institute: University of Kaposvár
animal husbandry
Doctoral School of Animal Science

Thesis supervisor: Veronika Halas
co-supervisor: Judit Szabó-Fodor
Location of studies (in Hungarian): Kaposvár University, Faculty of Agricultural and Environmental Sciences, Department of Animal Nutrition
Abbreviation of location of studies: AKKLT


Description of the research topic:

Above the tolerable level mycotoxin contamination of animal feeds results in depressed production and aids to – mainly complex etiology – diseases. Fumonizines occur in corn World-wide, therefore in course of feeding corn based diets the exposure is likely inevitable. In pigs FB1 causes primarily pulmonary oedema, however, it has not been clearly explored if the toxin affects the structural and functional properties of the digestive system.
The scopes of the PhD program are the following:
- evaluation of the effect of dietary FB1 content on the ileal and total tract digestibility of nutrients, as well as the digestible and metabolizable energy content of the feed in weaned piglets. In the course of studies the digestibility of macronutrients (crude protein, crude fat, crude fiber, starch, ash), amino acids and trace minerals are in focus.
- whether dietary FB1 content influences the structural and functional properties of the intestine, morphology of different segments of the gut epithelia and the gut permeability ex vivo.
- Evaluation of the absorption kinetics of FB1 in ex vivo studies.

Recommended language skills (in Hungarian): angol
Number of students who can be accepted: 1

Deadline for application: 2018-06-10


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )