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Thesis topic proposal
 
Krisztián Kvell
Differences in tissue senescence: lessons from thymic and pulmonary contexts

THESIS TOPIC PROPOSAL

Institute: University of Pécs
theoretical medicine
Doctoral School of Basic Medicine

Thesis supervisor: Krisztián Kvell
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK


Description of the research topic:

Different organs reach their functional apex at various ages, following which their senescence begins, although with various pace and mechanism. For example the thymus begins to age right following puberty, while the central nervous system begins to decline after approx. 24 years of age and the skeletal system begins to degenerate after approx. 30 years of age. For other organs (i. e. the lungs) the time-point of functional peak is more challenging to define. However, deciphering the relevant molecular mechanisms may shed light on such macroscopic differences. Our research group (with the supervision of Prof. Judit Pongracz and Dr. Krisztian Kvell) aims to discover molecular differences responsible for desynchronized organ senescence through comparing senescence in two rather different tissues: the thymic and the pulmonary context.

Number of students who can be accepted: 1

Deadline for application: 2018-05-18


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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