Thesis supervisor: András Komócsi
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
Autoimmune disorders frequently lead to dysfunction of cardiovascular system, and early atherosclerosis. These have important impact on the prognosis. This excess in mortality is rarely can be explained by conventional risk factors. In several cases even treatment of the autoimmune mechanisms may have adverse impact on the cardiovascular system. Clarification of relations may provide important information to better prognosis assessment, early screening of high risk cases and better treatment algorithms. Diagnostic modalities already available at the Heart Centre (tissue Doppler imaging, vascular ultrasound, arterial stiffness measurement, Holter ECG system, and complete invasive haemodynamic assessment) together with cardiac MR imaging provide opportunities the use of contemporary research methods. Cooperation with the Rheumatology and Immunology Clinic helps the interdisciplinary approach. So far several publications characterizing the cardiopulmonary in systemic sclerosis have been published based on this cooperation.