ODT - THESIS TOPIC: Judit Pongrácz: Test system development for ...


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Thesis topic proposal

Test system development for petide based drug delivery via the human lung using primary human lung tissue model

THESIS TOPIC PROPOSAL

Institute: University of Pécs
pharmaceutics
Doctoral School of Pharmacologycal and Pharmaceutical Sciences

Thesis supervisor: Judit Pongrácz
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

It is important to find optimized methods to deliver peptide based drugs to treat lung diseases or to administer these drugs systemically via the lung. PEPT1 and PEPT2 have been cloned from human tissues. PEPT2 is present in the human lung. PEPT2 is integrated into the cell membrane and has 12 membrane-spanning domain. PEPT2 is present in the bronchial epithelium, and the alveolar epitélium type II. Expression pattern, modulation of expression application in drug delivery will be tested using a lung model.

Number of students who can be accepted: 1

Deadline for application: 2018-05-18

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).