Thesis topic proposal
Ferenc Fülöp
Enikő Forró
Development of new enzyme-catalysed dinamic kinetic resolution for the preparation of pharmaceutically and chemically important enantiomers


Institute: University of Szeged
Doctoral School of Pharmaceutical Sciences

Thesis supervisor: Enikő Forró
co-supervisor: Ferenc Fülöp
Location of studies (in Hungarian): Szeged
Abbreviation of location of studies: SZ

Description of the research topic:

Development of new enzyme-catalysed dinamic kinetic resolution strategies for the preparation of enantiomeric beta-amino acids, important from both pharmacological and chemical aspects. Investigation of the enzymatic hydrolysis of racemic beta-amino esters in water and in organic solvents. Development and optimization of the enzymatic reactions in a solvent-free system. Study of potentially of substrate engineering.

Required language skills: fluent english
Number of students who can be accepted: 1

Deadline for application: 2018-06-30

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