Thesis supervisor: Zoltán Varga
Location of studies (in Hungarian): Research Centre for Natural Sciences Abbreviation of location of studies: MTA
Description of the research topic:
The medical application of nanoparticles ranges from their utilization in therapy and diagnostics, which includes the targeted delivery of various drugs as well as their use in molecular diagnostics. The current topic relates to the application of gold nanoparticles in the latter field. The goal of the research work is the biocompatible surface modification and functionalization of gold nanoparticles with peptides and oligonucleotides and their in vitro testing for the diagnosis of various cancers by molecular imaging and genetic mutations.
The planned work includes acquiring the necessary skills in preparative nanochemistry as well as in the measurement methods (DLS, TEM, FTIR, SAXS) for the thorough physico-chemical characterization of the nanoparticles. Additionally, the in vitro testing of the functionalized nanoparticles in cell cultures is also part of the PhD project.
Required language skills: English (fluent) Further requirements: Basic knowledge in colloid chemsitry and biochemistry, good communication skills, both oral and written english, ability to work in a group, as well as independently
Number of students who can be accepted: 1
Deadline for application: 2017-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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