Thesis supervisor: Csaba Vizler
Location of studies (in Hungarian): Institute of Biochemistry, BRC of HAS Abbreviation of location of studies: SzBK
Description of the research topic:
SUMMARY
Malignant tumors are inherently genetically instable and heterogeneous. In advanced carcinoma, circulating tumor cells may appear in the blood. If cancer therapy is successful, the number of circulating tumor cells drops. This phenomenon may help therapeutic decisions. These rare cells (even in advanced cases, a couple of cells/ml blood) might also be used for therapeutic decision, but it is still not clear how they represent the primary tumor and the metastases. Our aims are: A) investigating the viability, genetic variability and metastatic potential of human circulating tumor cells, B) studying the communication between the malignant cells and the tumor connective tissue matrix, C) setting up new animal models for studying agents and interventions targeting circulating tumor cells and metastasis formation.
Required language skills: English Further requirements: mammalian tissue culter and/or animal experimentation
Number of students who can be accepted: 1
Deadline for application: 2016-12-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
Login
