Thesis topic proposal
The role of the prion protein in the progression of transmissible spongiform degenerations


Institute: University of Szeged
theoretical medicine
Graduate School of Multidisciplinar Medical Scienses

Thesis supervisor: Ervin Welker
Location of studies (in Hungarian): Institute of Biochemistry, BRC
Abbreviation of location of studies: SZBK

Description of the research topic:

Transmissible spongiform encephalopathies (TSE-s) are fatal neurodegenerative disorders of which primary symptoms usually include progressive dementia and ataxia, associated with spongiform degeneration of the brain and accumulation of an abnormal protease-resistant form of the prion protein (PrPres) in the central nervous system. Our aim is to discern how the formation of this abnormal form is associated with the neuronal cell death that is evident in this disease.

Required language skills: English
Number of students who can be accepted: 1

Deadline for application: 2017-07-31

All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )