Thesis topic proposal
Ferenc Fülöp
Synthesis of alicyclic analogues of quinazoline-based alkaloids


Institute: University of Szeged
Doctoral School of Pharmaceutical Sciences

Thesis supervisor: Ferenc Fülöp
co-supervisor: Márta Palkó
Location of studies (in Hungarian): Szeged
Abbreviation of location of studies: SZTE

Description of the research topic:

Quinazolines represent a class of privileged scaffolds that occur in naturally occuring alkaloids, some of which exhibit a wide range of biological and pharmacological activities. These quinazolin-4(3H)-one based alkaloids attracted our attention not only due to their promising pharmacological properties but also their intriguing chemical structures. Moreover, as part of our ongoing pharmaceutical chemistry related programs or present aims are the synthesis of their alicyclic analogues. Our research program is directed towards: (a) Synthesis of heterocyclic compounds across ring-closing reactions by starting from unsaturated bicyclic amino acid derivatives.(b) Investigation of the retro-Diels Alder reactions of the synthesized heterocycles.

Required language skills: fluent english
Recommended language skills (in Hungarian): fluent english
Number of students who can be accepted: 1

Deadline for application: 2021-05-01

All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )