Thesis supervisor: Péter Lőw
Location of studies (in Hungarian): Eötvös Loránd University, Department of Anatomy, Cell and Developmental Biology Abbreviation of location of studies: ELTE
Description of the research topic:
We recently identified several critical factors for the fusion of secretory granules with lysosomes in a process known as crinophagy. In particular, the small GTPase Rab7 and the SNARE protein Syntaxin 13 may be recruited to secretory granules to make them competent for fusion with lysosomes in Drosophila salivary gland cells. This project aims to identify the molecular mechanisms of how these factors are targeted to secretory vesicles using a combination of molecular genetic, biochemichal and microscopy approaches.
Required language skills: fluent English (at least B2) Further requirements: MSc degree in biology or a related topic