Thesis supervisor: László Magor Lőrincz
Location of studies (in Hungarian): University of Szeged, Department of Physiology, Anatomy and Neuroscience, Szeged, Közép fasor 52. Abbreviation of location of studies: SzTE
Description of the research topic:
Absence seizures are bilateral generalized non colvulsive seizures, but the exact origin of its generation has remained elusive Using the most acknowlegded animal model of absence epilepsy, the GAERS rats (Genetic Absence Epilepsy Rats from Strassbourg) we have previously shown that specific interaction between various thalamic and cortical neurons leads to their generation, but the role of various cortical and thalamic neuron types is less known. Using electrophysiological techniques (single unit recording from identified neurons) in awake behaving rats we will scrutinize the activity of various cortical and thalamic neurons in the generation of absence seizures. The results could further our understanding of mechanisms involved in the generation of pathological thalamocortical activity.
Required language skills: English B2 Further requirements: minimum good PC user skills, science diploma, excellent problem solving skills
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