Tamás Hegedűs - ODT Personal data sheet


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Personal data sheet

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VALIDITY EXPIRED
personal data approved: 2020. IX. 24.

Personal data

name	Tamás Hegedűs
name of institution	Eötvös Loránd University, Budapest Pázmány Péter Catholic University, Budapest Semmelweis University, Budapest
doctoral school	ELTE Doctoral School of Biology (Academic staff member Az oktató a doktori iskola doktoranduszai számára oktat tantárgyat, és/vagy a doktori iskola megszavazta, hogy doktoranduszok számára kutatási témát írjon ki. ) PPKE Roska Tamás Doctoral School of Sciences and Technology (Academic staff member Az oktató a doktori iskola doktoranduszai számára oktat tantárgyat, és/vagy a doktori iskola megszavazta, hogy doktoranduszok számára kutatási témát írjon ki. ) SE Doctoral School of Basic and Translational Medicine (Academic staff member Az oktató a doktori iskola doktoranduszai számára oktat tantárgyat, és/vagy a doktori iskola megszavazta, hogy doktoranduszok számára kutatási témát írjon ki. ) SE Doctoral School of University Semmelweis (Supervisor Az oktató valamelyik doktori iskolában egy vagy több doktorandusz vagy doktorjelölt munkáját irányítja. )
the share of work in the different doctoral schools.	ELTE Doctoral School of Biology 33% PPKE Roska Tamás Doctoral School of Sciences and Technology 33% SE Doctoral School of University Semmelweis 34%
accreditation statement submitted to:	Eötvös Loránd University, Budapest

Contact details
E-mail address	tamashegelab.org
phone number	+36 1 459-1500/60230
	own web page

Academic title
scientific degree, title	Ph.D.
year degree was obtained	2003
discipline to which degree belongs	biology
institution granting the degree	ELTE (to be translated)

Employment
2017 -	Semmelweis University, Budapest egyetemi kutató
2012 -	MTA-SE Molekuláris Biofizikai Kutatócsoport (research institute, not university) other (not specified) (főmunkatárs)

Thesis topic supervisor

number of doctoral students supervised until now

number of students who fulfilled course requirements

0.5

students who obtained their degrees:

(50%)	Bianka Vivien Farkas	PhD	2023	PPCU-RTDS
	Hajnalka Budai-Sarankó	PhD	2017	DSB-ELTE

present PhD students:

Karen Odalys Torres Constante

(PhD)

(2026/08)

SEDI (to be translated)

hiányos adatú hallgatói:

Georgina Gáspárné Csizmadia

PhD

(2023/08)

SEDI (to be translated)

Thesis topic proposals

Research
research area	Investigation of the structure and dynamics of ABC proteins including multidrug transporters and the Cystic Fibrosis Transmembrane Conductance Regulator.
research field in which current research is conducted	biology physics

Publications

2020

Farkas Bianka, Csizmadia Georgina, Katona Eszter, Tusnády Gábor E, Hegedűs Tamás: MemBlob database and server for identifying transmembrane regions using cryo-EM maps, BIOINFORMATICS 36: (8) pp. 2595-2598.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL

2019

Farkas Bianka, Tordai Hedvig, Padányi Rita, Tordai Attila, Gera János, Paragi Gábor, Hegedűs Tamás: Discovering the chloride pathway in the CFTR channel, CELLULAR AND MOLECULAR LIFE SCIENCES 0: p. 0.
type of document: Journal paper/Article
language: English
URL

2018

Csizmadia Georgina, Farkas Bianka, Spagina Zoltán, Tordai Hedvig, Hegedűs Tamás: Quantitative comparison of ABC membrane protein type I exporter structures in a standardized way, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 16: pp. 396-403.
type of document: Journal paper/Article
language: English
URL

2016

Macalou S, Robey RW, Jabor Gozzi G, Shukla S, Grosjean I, Hegedus T, Ambudkar SV, Bates SE, Di Pietro A: The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport, CELLULAR AND MOLECULAR LIFE SCIENCES 73: (9) pp. 1927-1937.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL

2016

László L, Sarkadi B, Hegedüs T: Jump into a new fold-A homology based model for the ABCG2/BCRP multidrug transporter, PLOS ONE 11: (10) e0164426
type of document: Journal paper/Article
number of independent citations: 16
language: English
URL

2014

Veit G, Avramescu RG, Perdomo D, Phuan PW, Bagdany M, Apaja PM, Borot F, Szollosi D, Wu YS, Finkbeiner WE, Hegedus T, Verkman AS, Lukacs GL: Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression, SCIENCE TRANSLATIONAL MEDICINE 6: (246) 246ra97
type of document: Journal paper/Article
number of independent citations: 138
language: English
URL

2013

Okiyoneda T, Veit G, Dekkers J F, Bagdany M, Soya N, Xu H, Roldan A, Verkman A S, Kurth M, Simon A, Hegedus T, Beekman J M, Lukacs G L: Mechanism-based corrector combination restores ΔF508-CFTR folding and function., NATURE CHEMICAL BIOLOGY 9: (7) pp. 444-454.
type of document: Journal paper/Article
number of independent citations: 178
language: English
URL

2012

Gyimesi G, Borsodi D, Saranko H, Tordai H, Sarkadi B, Hegedus T: ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application., HUMAN MUTATION 33: (11) pp. 1547-1556.
type of document: Journal paper/Article
number of independent citations: 16
language: English
URL

2008

Hegedus T, Serohijos AW, Dokholyan NV, He L, Riordan JR: Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR., JOURNAL OF MOLECULAR BIOLOGY 378: (5) pp. 1052-1063.
type of document: Journal paper/Article
number of independent citations: 34
language: English
URL

2002

Hegedus T, Orfi L, Seprodi A, Varadi A, Sarkadi B, Keri G: Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1., BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1587: (2-3) pp. 318-325.
type of document: Journal paper/Review paper
number of independent citations: 140
language: English
DOI

Number of independent citations to these publications:

526

Scientometric data

Saját közlemény- és idézőlista

list of publications and citations

number of scientific publications that meet accreditation criteria:

number of scientific publications:

monographs and professional books:

monographs/books in which chapters/sections were contributed:

number of independent citations to scientific publications and creative works:

2751

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).