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personal data approved: 2019. XII. 09.
Personal data
name Balázs Hegedűs
name of institution
doctoral school
ELTE Doctoral School of Physics (Academic staff member)
SE Doctoral School of Clinical Medicine (Announcer of research topic)
SE Doctoral School of Pathological Sciences (Supervisor)
the share of work in the different doctoral schools. SE Doctoral School of Clinical Medicine 50%
SE Doctoral School of Pathological Sciences 50%
Contact details
E-mail address hegbalyahoo.com
phone number +36 1 215-6921
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2002
discipline to which degree belongs theoretical medicine
institution granting the degree Semmelweis Egyetem (to be translated)
Employment
2008 - Semmelweis University, Budapest
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 3.5
number of students who fulfilled course requirements 1.5
students who obtained their degrees:
Eszter Molnár PhD 2019  DSPS2-SE
(50%) Zoltán Lohinai PhD 2016  DSCM-SE
Tamás Garay PhD 2014  DSPS2-SE
(50%) Judit Berta PhD 2013  DSPS2-SE

students with degree granting in process:
Ágnes Júlia Bilecz PhD (2019/08)  DSPS2-SE
present PhD students:
Dominika Rittler (PhD) (2020/08)  DSPS2-SE
hiányos adatú hallgatói:
Ágnes Júlia Bilecz PhD ()  DSPS2-SE
  Thesis topic proposals
Research
research area Mechanism of tumor progression: cell migration, invasion, vascularization and metastasis. In vitro and in vivo preclinical models of anticancer therapy. Identification of novel predictive biomarkers.
research field in which current research is conducted theoretical medicine
biology
Publications
2019

Rittler Dominika, Baranyi Marcell, Molnár Eszter, Garay Tamás, Jalsovszky István, Varga Károly Imre, Hegedűs Luca, Aigner Clemens, Tóvári József, Tímár József, Hegedűs Balázs: The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20: (19) p. 4917.
type of document: Journal paper/Article
language: English
URL 
2018

Molnar E, Rittler D, Baranyi M, Grusch M, Berger W, Dome B, Tovari J, Aigner C, Timar J, Garay T, Hegedus B: Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells, BMC CANCER 18: (1) 542
type of document: Journal paper/Article
language: English
URL 
2017

Lohinai Z, Klikovits T, Moldvay J, Ostoros G, Raso E, Tímár J, Fábián K, Kovalszky I, Kenessey I, Aigner C, Rényi-Vámos F, Klepetko W, Dome B, Hegedűs B: KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS-mutation and bone metastasis, SCIENTIFIC REPORTS 7: 39721
type of document: Journal paper/Article
number of independent citations: 11
language: English
URL 
2017

Virág J, Haberler C, Baksa G, Piurkó V, Hegedüs Z, Reiniger L, Bálint K, Chocholous M, Kiss A, Lotz G, Glasz T, Schaff Zs, Garami M, Hegedűs B: Region specific differences of claudin-5 expression in pediatric intracranial ependymomas: Potential prognostic role in supratentorial cases, PATHOLOGY AND ONCOLOGY RESEARCH 23: (2) pp. 245-252.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2015

Garay T, Molnar E, Juhasz E, Laszlo V, Barbai T, Dobos J, Schelch K, Pirker C, Grusch M, Berger W, Timar J, Hegedus B: Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations, PATHOLOGY AND ONCOLOGY RESEARCH 21: (4) pp. 957-968.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2015

Garay T, Kenessey I, Molnar E, Juhasz E, Reti A, Laszlo V, Rozsas A, Dobos J, Dome B, Berger W, Klepetko W, Tovari J, Timar J, Hegedus B: Prenylation Inhibition-Induced Cell Death in Melanoma: Reduced Sensitivity in BRAF Mutant/PTEN Wild-Type Melanoma Cells., PLOS ONE 10: (2) e0117021
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2013

Garay T, Juhasz E, Molnar E, Eisenbauer M, Czirok A, Dekan B, Laszlo V, Hoda MA, Dome B, Timar J, Klepetko W, Berger W, Hegedus B: Cell migration or cytokinesis and proliferation? - revisiting the "go or grow" hypothesis in cancer cells in vitro., EXPERIMENTAL CELL RESEARCH 319: (20) pp. 3094-3103.
type of document: Journal paper/Article
number of independent citations: 29
language: English
URL 
2008

Hegedus B, Banerjee D, Yeh TH, Rothermich S, Perry A, Rubin JB, Garbow JR, Gutmann DH: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma., CANCER RESEARCH 68: (5) pp. 1520-1528.
type of document: Journal paper/Article
number of independent citations: 36
language: English
URL 
2007

Hegedus B, Dasgupta B, Shin JE, Emnett RJ, Hart-Mahon EK, Elghazi L, Bernal-Mizrachi E, Gutmann DH: Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms., CELL STEM CELL 1: (4) pp. 443-457.
type of document: Journal paper/Article
number of independent citations: 79
language: English
URL 
2006

Hegedus B, Marga F, Jakab K, Sharpe-Timms KL, Forgacs G: The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors, BIOPHYSICAL JOURNAL 91: (7) pp. 2708-2716.
type of document: Journal paper/Article
number of independent citations: 56
language: English
URL 
Number of independent citations to these publications:221 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
116
number of scientific publications:
116
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
2107

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )