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Personal data sheet
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personal data approved: 2018. IV. 09.
Personal data
name Balázs Hegedűs
name of institution
doctoral school
ELTE Doctoral School of Physics (Academic staff member)
SE Doctoral School of Clinical Medicine (Announcer of research topic)
SE Doctoral School of Pathological Sciences (Supervisor)
the share of work in the different doctoral schools. SE Doctoral School of Clinical Medicine 50%
SE Doctoral School of Pathological Sciences 50%
Contact details
E-mail address hegbalyahoo.com
phone number +36 1 215-6921
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2002
discipline to which degree belongs theoretical medicine
institution granting the degree Semmelweis Egyetem (to be translated)
Employment
2008 - Semmelweis University, Budapest
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 3.5
number of students who fulfilled course requirements 1.5
students who obtained their degrees:
(50%) Zoltán Lohinai PhD 2016  DSCM-SE
Tamás Garay PhD 2014  DSPS2-SE
(50%) Judit Berta PhD 2013  DSPS2-SE
students with degree granting in process:
Ágnes Júlia Bilecz PhD (2019/08)  DSPS2-SE
Eszter Molnár PhD (2018/10)  DSPS2-SE
present PhD students:
Dominika Rittler (PhD) (2018/08)  DSPS2-SE
  Thesis topic proposals
Research
research area Mechanism of tumor progression: cell migration, invasion, vascularization and metastasis. In vitro and in vivo preclinical models of anticancer therapy. Identification of novel predictive biomarkers.
research field in which current research is conducted theoretical medicine
biology
Publications
2017

 Lohinai Z, Klikovits T, Moldvay J, Ostoros G, Raso E, Tímár J, Fábián K, Kovalszky I, Kenessey I, Aigner C, Rényi-Vámos F, Klepetko W, Dome B, Hegedűs B: KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS-mutation and bone metastasis, SCIENTIFIC REPORTS 7: Paper 39721. 8 p.
type of document: Journal paper/Article
language: English
DOI 
2017

 Virág J, Haberler C, Baksa G, Piurkó V, Hegedüs Z, Reiniger L, Bálint K, Chocholous M, Kiss A, Lotz G, Glasz T, Schaff Zs, Garami M, Hegedűs B: Region specific differences of claudin-5 expression in pediatric intracranial ependymomas, PATHOLOGY AND ONCOLOGY RESEARCH Online First: p. In press. 8 p.
type of document: Journal paper/Article
language: English
DOI 
2017

 Hegedus L, Garay T, Molnar E, Varga K, Bilecz A, Torok S, Padanyi R, Paszty K, Wolf M, Grusch M, Kallay E, Dome B, Berger W, Hegedus B, Enyedi A: The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells., INTERNATIONAL JOURNAL OF CANCER &: p. &.
type of document: Journal paper/Article
language: English
DOI 
2015

 Garay T, Kenessey I, Molnar E, Juhasz E, Reti A, Laszlo V, Rozsas A, Dobos J, Dome B, Berger W, Klepetko W, Tovari J, Timar J, Hegedus B: Prenylation Inhibition-Induced Cell Death in Melanoma: Reduced Sensitivity in BRAF Mutant/PTEN Wild-Type Melanoma Cells., PLOS ONE 10: (2) Paper e0117021. 18 p.
type of document: Journal paper/Article
number of independent citations: 2
language: English
DOI 
2013

 Garay T, Juhasz E, Molnar E, Eisenbauer M, Czirok A, Dekan B, Laszlo V, Hoda MA, Dome B, Timar J, Klepetko W, Berger W, Hegedus B: Cell migration or cytokinesis and proliferation? - revisiting the "go or grow" hypothesis in cancer cells in vitro., EXPERIMENTAL CELL RESEARCH 319: (20) pp. 3094-3103.
type of document: Journal paper/Article
number of independent citations: 12
language: English
URL 
2008

 Hegedus B, Yeh TH, Lee da Y, Emnett RJ, Li J, Gutmann DH: Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis., HUMAN MOLECULAR GENETICS 17: (19) pp. 2956-2966.
type of document: Journal paper/Article
number of independent citations: 4
language: English
2008

 Hegedus B, Banerjee D, Yeh TH, Rothermich S, Perry A, Rubin JB, Garbow JR, Gutmann DH: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma., CANCER RESEARCH 68: (5) pp. 1520-1528.
type of document: Journal paper/Article
number of independent citations: 23
language: English
DOI 
2007

 Hegedus B, Dasgupta B, Shin JE, Emnett RJ, Hart-Mahon EK, Elghazi L, Bernal-Mizrachi E, Gutmann DH: Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms., CELL STEM CELL 1: (4) pp. 443-457.
type of document: Journal paper/Article
number of independent citations: 32
language: English
DOI 
2006

 Hegedus B, Marga F, Jakab K, Sharpe-Timms KL, Forgacs G: The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors, BIOPHYSICAL JOURNAL 91: (7) pp. 2708-2716.
type of document: Journal paper/Article
number of independent citations: 36
language: English
DOI 
2004

 Hegedus B, Zach J, Czirok A, Lovey J, Vicsek T: Irradiation and Taxol treatment result in non-monotonous, dose-dependent changes in the motility of glioblastoma cells, JOURNAL OF NEURO-ONCOLOGY 67: pp. 147-157.
type of document: Journal paper/Article
number of independent citations: 29
language: English
DOI 
Number of independent citations to these publications:138 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
87
number of scientific publications:
98
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
1381

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )