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personal data approved: 2021. XII. 15.
Personal data
Lóránt Székvölgyi
name Lóránt Székvölgyi
name of institution
doctoral school
DE Doctoral School of Pharmaceutical Sciences (Academic staff member)
DE Doctoral School of Molecular Cellular and Immune Biology (Supervisor)
the share of work in the different doctoral schools. DE Doctoral School of Pharmaceutical Sciences 20%
DE Doctoral School of Molecular Cellular and Immune Biology 80%
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address lorantszmed.unideb.hu
phone number +36 52 411-717
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2007
discipline to which degree belongs theoretical medicine
institution granting the degree University of Debrecen
scientific degree, title Habilitation
year degree was obtained 2019
discipline to which degree belongs theoretical medicine
institution granting the degree University of Debrecen
Employment
2007 - University of Debrecen
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 5
number of students who fulfilled course requirements 3
students who obtained their degrees:
László Halász PhD 2019  DSMCI
Szabolcs Hetey PhD 2019  DSMCI

completed course requirement:
Beáta Boros-Oláh (PhD) 2021/08  DSMCI
present PhD students:
Lilla Hornyák (PhD) (2024/08)  DSMCI
  Thesis topic proposals
Research
research area Chromatin structure and pathological gene rearrangements Epigenetic regulation of homologous recombination
research field in which current research is conducted theoretical medicine
biology
Publications
2021

Miskei Márton, Horváth Adrienn, Viola Lívia, Varga Laura, Nagy Éva, Feró Orsolya, Karányi Zsolt, Roszik Jason, Miskey Csaba, Ivics Zoltán, Székvölgyi Lóránt: Genome-wide mapping of binding sites of the transposase-derived SETMAR protein in the human genome, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
type of document: Journal paper/Article
language: English
URL 
2020

Karányi Zsolt, Hornyák Lilla, Székvölgyi Lóránt: Histone H3 lysine 56 acetylation is required for formation of normal levels of meiotic DNA breaks in S. cerevisiae, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 7: 364
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2019

Boros-Oláh Beáta, Dobos Nikoletta, Hornyák Lilla, Szabó Zoltán, Karányi Zsolt, Halmos Gábor, Roszik Jason, Székvölgyi Lóránt: Drugging the R-loop interactome: RNA-DNA hybrid binding proteins as targets for cancer therapy, DNA REPAIR 84: 102642
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL 
2018

Hornyák Lilla, Dobos Nikoletta, Koncz Gábor, Karányi Zsolt, Páll Dénes, Szabó Zoltán, Halmos Gábor, Székvölgyi L: The role of indoleamine-2,3-dioxygenase in cancer development, diagnostics, and therapy, FRONTIERS IN IMMUNOLOGY 9: 151
type of document: Journal paper/Review paper
number of independent citations: 165
language: English
URL 
2018

Hegedüs É, Kókai E, Nánási P, Imre L, Halász L, Jossé R, Antunovics Zs, Webb MR, Hage AE, Pommier Y, Székvölgyi L, Dombrádi V, Szabó G: Endogenous single-strand DNA breaks at RNA polymerase II promoters in Saccharomyces cerevisiae, NUCLEIC ACIDS RESEARCH 46: (20) pp. 10649-10668.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2018

Karányi Zsolt, Halász László, Acquaviva Laurent, Jónás Dávid, Hetey Szabolcs, Boros-Oláh Beáta, Peng Feng, Chen Doris, Klein Franz, Géli Vincent, Székvölgyi Lóránt: Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation., JOURNAL OF CELL BIOLOGY 217: (10) pp. 3398-3415.
type of document: Journal paper/Article
number of independent citations: 6
language: English
URL 
2017

Halász László, Karányi Zsolt, Boros-Oláh Beáta, Rózsa Tímea, Sipos Éva, Nagy Éva, Mosolygó-L Ágnes, Mázló Anett, Rajnavölgyi Éva, Halmos Gábor, Székvölgyi Lóránt: RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases, GENOME RESEARCH 27: (6) pp. 1063-1073.
type of document: Journal paper/Article
number of independent citations: 52
language: English
URL 
2017

Szabolcs Hetey, Beáta Boros-Oláh, Tímea Kuik-Rózsa, Qiuzhen Li, Zsolt Karányi, Zoltán Szabó, Jason Roszik, Nikoletta Szalóki, György Vámosi, Katalin Tóth, Lóránt Székvölgyi: Biophysical characterization of histone H3.3 K27M point mutation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 490: (3) pp. 868-875.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2015

Lorant Szekvolgyi, Kunihiro Ohta, Alain Nicolas: Initiation of meiotic homologous recombination: Flexibility, impact of histone modifications, and chromatin remodeling, COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY 7: (5) a016527
type of document: Journal paper/Article
number of independent citations: 36
language: English
URL 
2013

Acquaviva L, Szekvolgyi L, Dichtl B, Dichtl BS, Saint Andre CD, Nicolas A, Geli V: The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination, SCIENCE 339: (6116) pp. 215-218.
type of document: Journal paper/Article
number of independent citations: 158
language: English
URL 
Number of independent citations to these publications:437 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
34
number of scientific publications:
34
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
1 
scientific publications published abroad that meet the accreditation criteria:
33
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
0
number of independent citations to scientific publications and creative works:
740

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )