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personal data approved: 2020. IX. 24.
Personal data
Tamás Hegedűs
name Tamás Hegedűs
name of institution
doctoral school
ELTE Doctoral School of Biology (Academic staff member)
PPKE Roska Tamás Doctoral School of Sciences and Technology (Supervisor)
SE Doctoral School of Basic and Translational Medicine (Supervisor)
the share of work in the different doctoral schools. ELTE Doctoral School of Biology 33%
PPKE Roska Tamás Doctoral School of Sciences and Technology 33%
SE Doctoral School of Basic and Translational Medicine 34%
accreditation statement submitted to: Eötvös Loránd University, Budapest
Contact details
E-mail address tamashegelab.org
phone number +36 1 459-1500/60230
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2003
discipline to which degree belongs biology
institution granting the degree ELTE (to be translated)
Employment
2017 - Semmelweis University, Budapest
egyetemi kutató
2012 - MTA-SE Molekuláris Biofizikai Kutatócsoport (research institute, not university)
other (not specified) (főmunkatárs)
Thesis topic supervisor
number of doctoral students supervised until now 3
number of students who fulfilled course requirements 0.5
students who obtained their degrees:
Hajnalka Budai-Sarankó PhD 2017  DSB-ELTE

present PhD students:
Georgina Gáspárné Csizmadia (PhD) (2022/08)  DSBM-SE
(50%) Bianka Vivien Farkas (PhD) (2022/01)  PPCU-RTDS
  Thesis topic proposals
Research
research area Investigation of the structure and dynamics of ABC proteins including multidrug transporters and the Cystic Fibrosis Transmembrane Conductance Regulator.
research field in which current research is conducted biology
physics
Publications
2020

Farkas Bianka, Csizmadia Georgina, Katona Eszter, Tusnády Gábor E, Hegedűs Tamás: MemBlob database and server for identifying transmembrane regions using cryo-EM maps, BIOINFORMATICS 36: (8) pp. 2595-2598.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2019

Farkas Bianka, Tordai Hedvig, Padányi Rita, Tordai Attila, Gera János, Paragi Gábor, Hegedűs Tamás: Discovering the chloride pathway in the CFTR channel, CELLULAR AND MOLECULAR LIFE SCIENCES 0: p. 0.
type of document: Journal paper/Article
language: English
URL 
2018

Csizmadia Georgina, Farkas Bianka, Spagina Zoltán, Tordai Hedvig, Hegedűs Tamás: Quantitative comparison of ABC membrane protein type I exporter structures in a standardized way, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 16: pp. 396-403.
type of document: Journal paper/Article
language: English
URL 
2016

Macalou S, Robey RW, Jabor Gozzi G, Shukla S, Grosjean I, Hegedus T, Ambudkar SV, Bates SE, Di Pietro A: The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport, CELLULAR AND MOLECULAR LIFE SCIENCES 73: (9) pp. 1927-1937.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2016

László L, Sarkadi B, Hegedüs T: Jump into a new fold-A homology based model for the ABCG2/BCRP multidrug transporter, PLOS ONE 11: (10) e0164426
type of document: Journal paper/Article
number of independent citations: 16
language: English
URL 
2014

Veit G, Avramescu RG, Perdomo D, Phuan PW, Bagdany M, Apaja PM, Borot F, Szollosi D, Wu YS, Finkbeiner WE, Hegedus T, Verkman AS, Lukacs GL: Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression, SCIENCE TRANSLATIONAL MEDICINE 6: (246) 246ra97
type of document: Journal paper/Article
number of independent citations: 138
language: English
URL 
2013

Okiyoneda T, Veit G, Dekkers J F, Bagdany M, Soya N, Xu H, Roldan A, Verkman A S, Kurth M, Simon A, Hegedus T, Beekman J M, Lukacs G L: Mechanism-based corrector combination restores ΔF508-CFTR folding and function., NATURE CHEMICAL BIOLOGY 9: (7) pp. 444-454.
type of document: Journal paper/Article
number of independent citations: 178
language: English
URL 
2012

Gyimesi G, Borsodi D, Saranko H, Tordai H, Sarkadi B, Hegedus T: ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application., HUMAN MUTATION 33: (11) pp. 1547-1556.
type of document: Journal paper/Article
number of independent citations: 16
language: English
URL 
2008

Hegedus T, Serohijos AW, Dokholyan NV, He L, Riordan JR: Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR., JOURNAL OF MOLECULAR BIOLOGY 378: (5) pp. 1052-1063.
type of document: Journal paper/Article
number of independent citations: 34
language: English
URL 
2002

Hegedus T, Orfi L, Seprodi A, Varadi A, Sarkadi B, Keri G: Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1., BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1587: (2-3) pp. 318-325.
type of document: Journal paper/Review paper
number of independent citations: 140
language: English
DOI 
Number of independent citations to these publications:526 
Scientometric data
Saját közlemény- és idézőlista list of publications and citations
number of scientific publications that meet accreditation criteria:
71
number of scientific publications:
71
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
2 
number of independent citations to scientific publications and creative works:
2378

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )