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personal data approved: 2021. VI. 10.
Personal data
Csaba Tömböly
name Csaba Tömböly
name of institution
doctoral school
SzTE Theoretical Medicine Doctoral School (Supervisor)
SzTE Doctoral School of Chemistry (Academic staff member)
the share of work in the different doctoral schools. SzTE Theoretical Medicine Doctoral School 50%
SzTE Doctoral School of Chemistry 50%
Contact details
E-mail address tombolybrc.hu
phone number +36 62 599-646
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2001
discipline to which degree belongs theoretical medicine
institution granting the degree University of Szeged
Employment
2003 - MTA Szegedi Biológiai Kutatóközpont (research institute, not university)
other (not specified) (tudományos főmunkatárs)
Thesis topic supervisor
number of doctoral students supervised until now 4
number of students who fulfilled course requirements 1
students who obtained their degrees:
Szabolcs Dvorácskó PhD 2019  TMDS
Balázs Schäfer PhD 2015  TMDS

completed course requirement:
Gabriella Fiser (PhD) 2016/08  TMDS
present PhD students:
Judit Darusi (PhD) (2022/08)  TMDS
  Thesis topic proposals
Research
research area Preparation of specifically modified proteins by synthetic and semisynthetic strategies; fluorescent, stable and radioactive isotope labelling of small molecules, peptides and proteins
research field in which current research is conducted chemistry
biology
Publications
2020

Szűcs Edina, Marton János, Szabó Zoltán, Hosztafi Sándor, Kékesi Gabriella, Tuboly Gábor, Bánki László, Horváth Gyöngyi, Szabó Pál T., Tömböly Csaba, Varga Katalin Zsuzsanna, Benyhe Sándor, Ötvös Ferenc: Synthesis, biochemical, pharmacological characterization and in silico profile modelling of highly potent opioid orvinol and thevinol derivatives, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 191: 112145
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2019

Dvorácskó S., Keresztes A., Mollica A., Stefanucci A., Macedonio G., Pieretti S., Zádor F., Walter F.R., Deli M.A., Kékesi G., Bánki L., Tuboly G., Horváth G., Tömböly C.: Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 178: pp. 571-588.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2018

Bacsa Ildikó, Herman Bianka Edina, Jójárt Rebeka, Herman Kevin Stefan, Wölfling János, Schneider Gyula, Varga Mónika, Tömböly C, Rizner Tea Lanisnik, Szécsi Mihály, Mernyák Erzsébet: Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis, JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 33: (1) pp. 1271-1282.
type of document: Journal paper/Article
number of independent citations: 8
language: English
URL 
2018

De Prins A, Martin C, Van Wanseele Y, Skov LJ, Tomboly C, Tourwe D, Caveliers V, Van Eeckhaut A, Holst B, Rosenkilde MM, Smolders I, Ballet S: Development of potent and proteolytically stable human neuromedin U receptor agonists, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 144: pp. 887-897.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2016

Schafer B, Orban E, Fiser G, Marton A, Vizler C, Tomboly C: Semisynthesis of membrane-anchored cholesteryl lipoproteins on live cell surface by azide–alkyne click reaction, TETRAHEDRON LETTERS 57: (8) pp. 868-873.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2013

Schafer B, Orban E, Borics A, Huszar K, Nyeste A, Welker E, Tomboly C: Preparation of semisynthetic lipoproteins with fluorescent cholesterol anchor and their introduction to the cell membrane with minimal disruption of the membrane., BIOCONJUGATE CHEMISTRY 24: (10) pp. 1684-1697.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2008

Tomboly C, Ballet S, Feytens D, Kover KE, Borics A, Lovas S, Al-Khrasani M, Furst Z, Toth G, Benyhe S, Tourwe D: Endomorphin-2 with a beta-turn backbone constraint retains the potent mu-opioid receptor agonist properties, JOURNAL OF MEDICINAL CHEMISTRY 51: (1) pp. 173-177.
type of document: Journal paper/Article
number of independent citations: 26
language: English
URL 
2008

Keresztes A, Szucs M, Borics A, Kover KE, Forro E, Fulop F, Tomboly C, Peter A, Pahi A, Fabian G, Muranyi M, Toth G: New endomorphin analogues containing alicyclic beta-amino acids: Influence on bioactive conformation and pharmacological profile, JOURNAL OF MEDICINAL CHEMISTRY 51: (14) pp. 4270-4279.
type of document: Journal paper/Article
number of independent citations: 28
language: English
URL 
2007

Toth G, Ioja E, Tomboly C, Ballet S, Tourwe D, Peter A, Martinek T, Chung NN, Schiller PW, Benyhe S, Borsodi A: Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists, JOURNAL OF MEDICINAL CHEMISTRY 50: (2) pp. 328-333.
type of document: Journal paper/Article
number of independent citations: 11
language: English
URL 
2004

Tomboly C, Kover KE, Peter A, Tourwe D, Biyashev D, Benyhe S, Borsodi A, Al-Khrasani M, Ronai AZ, Toth G: Structure-activity study on the Phe side chain arrangement of endomorphins using conformationally constrained analogues, JOURNAL OF MEDICINAL CHEMISTRY 47: (3) pp. 735-743.
type of document: Journal paper/Article
number of independent citations: 39
language: English
URL 
Number of independent citations to these publications:127 
Scientometric data
Saját közlemény- és idézőlista list of publications and citations
number of scientific publications that meet accreditation criteria:
73
number of scientific publications:
73
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
809

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )