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personal data approved: 2021. XII. 02.
Personal data
name Orsolya Tőke
name of institution
doctoral school
BME George A. Olah Doctoral School of Chemistry and Chemical Technology (Academic staff member)
ELTE Doctoral School of Biology (Academic staff member)
the share of work in the different doctoral schools. BME George A. Olah Doctoral School of Chemistry and Chemical Technology 50%
ELTE Doctoral School of Biology 50%
Contact details
phone number +36 1 382-6575
Academic title
scientific degree, title Ph.D.
year degree was obtained 2002
discipline to which degree belongs chemistry
institution granting the degree Washington University, St. Louis, Missouri, USA (to be translated)
scientific degree, title Ph.D.
year degree was obtained 2006
discipline to which degree belongs chemistry
institution granting the degree ELTE TTK (honosítás) (to be translated)
Employment
2005 - Természettudományi Kutatóközpont
other (not specified) (tudományos főmnktrs)
Thesis topic supervisor
number of doctoral students supervised until now 1
number of students who fulfilled course requirements 1
students who obtained their degrees:
Gergő Horváth PhD 2016  DSB-ELTE

  Thesis topic proposals
Research
research area investigation of protein structure and dynamics by solution and solid-state NMR spectroscopy and molecular biology methodologies
research field in which current research is conducted chemistry
biology
Publications
2021

Tőke Orsolya, Koprivanacz Kitti, Radnai László, Merő Balázs, Juhász Tünde, Liliom Károly, Buday László: Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding, CELLS 10: (1) 173
type of document: Journal paper/Article
language: English
URL 
2020

Kirsch Klára, Zeke András, Tőke Orsolya, Sok Péter, Sethi Ashish, Sebő Anna, Kumar Ganesan Senthil, Egri Péter, Póti Ádám L., Gooley Paul, Peti Wolfgang, Bento Isabel, Alexa Anita, Reményi Attila: Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38, NATURE COMMUNICATIONS 11: (1) 5769
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2019

Horváth Gergő, Egyed Orsolya, Tang Changguo, Kovács Mihály, Micsonai András, Kardos József, Toke Orsolya: Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation, SCIENTIFIC REPORTS 9: 4825
type of document: Journal paper/Article
language: English
URL 
2017

Horvath G, Biczók László, Majer Zuzsanna, Kovács Mihály, Micsonai András, Kardos József, Tőke Orsolya: Structural insight into a partially unfolded state preceding aggregation in an intracellular lipid-binding protein, FEBS JOURNAL 284: (21) pp. 3637-3661.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2016

Horvath G, Bencsura A, Simon A, Tochtrop GP, DeKoster GT, Covey DF, Cistola DP, Toke O: Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR., FEBS JOURNAL 283: (3) pp. 541-555.
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL 
2012

Horváth G, Király P, Tárkányi G, Toke O: Internal motions and exchange processes in human ileal bile acid-binding protein as studied by backbone ^^15^^^N NMR spectroscopy, BIOCHEMISTRY 51: pp. 1848-1861.
type of document: Journal paper/Article
number of independent citations: 15
language: English
URL 
2007

Tőke O, Monsey JD, Cistola DP: Kinetic mechanism of ligand binding in human ileal bile acid binding protein as determined by stopped-flow fluorescence analysis, BIOCHEMISTRY 46: (18) pp. 5427-5436.
type of document: Journal paper/Article
number of independent citations: 13
language: English
URL 
2006

O Toke, G T DeKoster, J D Monsey, C Tang, D P Cistola: Determinants of Cooperativity and Site-Selectivity in Human Ileal Bile Acid-Binding Protein, BIOCHEMISTRY 45: pp. 727-737.
type of document: Journal paper/Article
number of independent citations: 37
language: English
URL 
2005

Toke O: Antimicrobial peptides: New candidates in the fight against bacterial infections, BIOPOLYMERS 80: pp. 717-735.
type of document: Journal paper/Review paper
number of independent citations: 213
language: English
URL 
2004

Toke O, Maloy WL, Kim SJ, Blazyk J, Schaefer J: Secondary structure and lipid contact of a peptide antibiotic in phospholipid bilayers by REDOR, BIOPHYSICAL JOURNAL 87: pp. 662-674.
type of document: Journal paper/Article
number of independent citations: 62
language: English
URL 
Number of independent citations to these publications:353 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
38
number of scientific publications:
38
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
1 
scientific publications published abroad that meet the accreditation criteria:
35
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
1
number of independent citations to scientific publications and creative works:
620

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )