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personal data approved: 2019. XI. 29.
Personal data
László Somsák
name László Somsák
name of institution
doctoral school
DE Doctoral School of Chemistry (Core member)
Council of the Doctoral School
DE 
Természettudományi Habilitációs Bizottság
the share of work in the different doctoral schools. DE Doctoral School of Chemistry 99%
DE KDI-DE Council of the Doctoral School 1%
accreditation statement submitted to: University of Debrecen
HAC accreditation
full compliance
(2019. VI. 28.)
Contact details
E-mail address somsak.laszloscience.unideb.hu
phone number +36 52 512-900/22348
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 1983
discipline to which degree belongs chemistry
institution granting the degree Kossuth Lajos Tudományegyetem, Debrecen (to be translated)
scientific degree, title DSc
year degree was obtained 2002
discipline to which degree belongs chemistry
institution granting the degree HAS
Employment
1978 - University of Debrecen
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 15
number of students who fulfilled course requirements 13
students who obtained their degrees:
Eszter Szennyes PhD 2019  KDI-DE
Erzsébet Katalin Szabó PhD 2018  KDI-DE
(50%) Tímea Kaszás PhD 2018  KDI-DE
András Páhi PhD 2014  KDI-DE
Sándor Kun PhD 2014  KDI-DE
Bálint Kónya PhD 2012  KDI-DE
Éva Bokor PhD 2010  KDI-DE
Nóra Felföldi PhD 2010  KDI-DE
Zsuzsa Hadady PhD 2007  KDI-DE
Katalin Margit Czifrák PhD 2005  KDI-DE
Veronika Nagy PhD 2004  KDI-DE
Viktor Gyóllai PhD 2003  KDI-DE
Marietta Vágvölgyiné Tóth PhD 2002  KDI-DE

present PhD students:
(50%) Mariann Kiss (PhD) (2020/08)  KDI-DE
Nándor Kánya (PhD) (2020/08)  KDI-DE
  Thesis topic proposals
Research
research area Transformations of carbohydrates by anomeric radicals, anions and carbenes; synthesis of C-glycosyl derivatives, glycals; design of glycoenzyme inhibitors, glycomimicks, antidiabetics.
research field in which current research is conducted chemistry
Publications
2019

Kaszás Tímea, Tóth Marietta, Langer Peter, Somsák László: C-Glycosyl Styrene Type Compounds by Pd-Catalyzed Cross-Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Benzyl Bromides, ADVANCED SYNTHESIS & CATALYSIS 361: (1) pp. 105-117.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2019

Barr Daniel, Szennyes Eszter, Bokor Éva, Al-Oanzi Ziad H., Moffatt Colin, Kun Sándor, Docsa Tibor, Sipos Ádám, Davies Matthew P., Mathomes Rachel T., Snape Timothy J., Agius Loranne, Somsák László, Hayes Joseph M.: Identification of C -β- d -Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies, ACS CHEMICAL BIOLOGY 14: pp. 1460-1470.
type of document: Journal paper/Article
language: English
URL 
2018

Eszter Szennyes, Éva Bokor, Peter Langer, Gyöngyi Gyémánt, Tibor Docsa, Ádám Sipos, László Somsák: The first general synthesis of 2-C-(β-D-glycopyranosyl)pyrimidines and their evaluation as inhibitors of some glycoenzymes, NEW JOURNAL OF CHEMISTRY 42: (21) pp. 17439-17446.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2017

Bokor Éva, Kun Sándor, Goyard David, Tóth Marietta, Praly Jean-Pierre, Vidal Sébastien, Somsák László: C‑Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential, CHEMICAL REVIEWS 117: (3) pp. 1687-1764.
type of document: Journal paper/Review paper
number of independent citations: 45
language: English
URL 
2017

Bokor Éva, Kyriakis Efthimios, Solovou Theodora G A, Koppány Csenge, Kantsadi Anastassia L, Szabó Katalin E, Szakács Andrea, Stravodimos George A, Docsa Tibor, Skamnaki Vassiliki T, Zographos Spyros E, Gergely Pál, Leonidas Demetres D, Somsák László: Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-D-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study., JOURNAL OF MEDICINAL CHEMISTRY 60: (22) pp. 9251-9262.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2008

Somsák L, Czifrák K, Tóth M, Bokor É, Chrysina E D, Alexacou K-M, Hayes J M, Tiraidis C, Lazoura E, Leonidas D D, Zographos S E, Oikonomakos N G: New inhibitors of glycogen phosphorylase as potential antidiabetic agents, CURRENT MEDICINAL CHEMISTRY 15: pp. 2933-2983.
type of document: Journal paper/Review paper
number of independent citations: 63
language: English
URL 
2003

Somsák L, Nagy V, Hadady Zs, Docsa T, Gergely P: Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: regent developments, CURRENT PHARMACEUTICAL DESIGN 9: pp. 1177-1189.
type of document: Journal paper/Article
number of independent citations: 189
language: English
URL 
2001

Somsak L, Kovacs L, Toth M, Osz E, Szilagyi L, Gyorgydeak Z, Dinya Z, Docsa T, Toth B, Gergely P: Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of D-gluco- and D-xylopyranosylidene-spiro-(thio)hydantoins and N-(D-glucopyranosyl) amides, JOURNAL OF MEDICINAL CHEMISTRY 44: pp. 2843-2848.
type of document: Journal paper/Article
number of independent citations: 105
language: English
URL 
2001

Somsak L: Carbanionic reactivity of the anomeric center in carbohydrates, CHEMICAL REVIEWS 101: (1) pp. 81-135.
type of document: Journal paper/Review paper
number of independent citations: 141
language: English
URL 
1993

SOMSAK L, NEMETH I: A SIMPLE METHOD FOR THE SYNTHESIS OF ACYLATED PYRANOID GLYCALS UNDER APROTIC CONDITIONS, JOURNAL OF CARBOHYDRATE CHEMISTRY 12: (4-5) pp. 679-684.
type of document: Journal paper/Article
number of independent citations: 67
language: English
URL 
Number of independent citations to these publications:616 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
349
number of scientific publications:
354
monographs and professional books:
1
monographs/books in which chapters/sections were contributed:
10 
number of independent citations to scientific publications and creative works:
2467
further relevant information regarding accreditation (in Hungarian)
Somsák, László (Ed.) Carbohydrate-spiro-heterocycles Springer, Svájc : Springer International Publishing (2019) , 299 pp. DOI ISBN: 9783030319410 ISBN: 9783030319427

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )