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personal data approved: 2022. XI. 02.
Personal data
László Somsák
name László Somsák
name of institution
doctoral school
DE Doctoral School of Chemistry (Core member emeritus)
Council of the Doctoral School
the share of work in the different doctoral schools. DE Doctoral School of Chemistry 99%
DE KDI-DE Council of the Doctoral School 1%
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address somsak.laszloscience.unideb.hu
phone number +36 52 512-900/22348
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 1983
discipline to which degree belongs chemistry
institution granting the degree Kossuth Lajos Tudományegyetem, Debrecen (to be translated)
scientific degree, title DSc
year degree was obtained 2002
discipline to which degree belongs chemistry
institution granting the degree HAS
Employment
2023 - University of Debrecen
professor emeritus
1978 - University of Debrecen
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 15
number of students who fulfilled course requirements 13
students who obtained their degrees:
(50%) Mariann Kiss PhD 2022  KDI-DE
Nándor Kánya PhD 2021  KDI-DE
Eszter Szennyes PhD 2019  KDI-DE
Erzsébet Katalin Szabó PhD 2018  KDI-DE
(50%) Tímea Kaszás PhD 2018  KDI-DE
András Páhi PhD 2014  KDI-DE
Sándor Kun PhD 2014  KDI-DE
Bálint Kónya PhD 2012  KDI-DE
Éva Bokor PhD 2010  KDI-DE
Nóra Felföldi PhD 2010  KDI-DE
Zsuzsa Hadady PhD 2007  KDI-DE
Katalin Margit Czifrák PhD 2005  KDI-DE
Veronika Nagy PhD 2004  KDI-DE
Viktor Gyóllai PhD 2003  KDI-DE
Marietta Vágvölgyiné Tóth PhD 2002  KDI-DE

present PhD students:
Alshimaa Ibrahim Zaki Ahmed Salama (PhD) (2025/08)  KDI-DE
Rahaf Akel (PhD) (2025/08)  KDI-DE
  Thesis topic proposals
Research
research area Transformations of carbohydrates by anomeric radicals, anions and carbenes; synthesis of C-glycosyl derivatives, glycals; design of glycoenzyme inhibitors, glycomimicks, antidiabetics.
research field in which current research is conducted chemistry
Publications
2021

Sipos Á, Szennyes E, Hajnal ÉN, Kun S, Szabó KE, Uray K, Somsák L, Docsa T, Bokor É: Dual-target compounds against type 2 Diabetes Mellitus: proof of concept for sodium dependent glucose transporter (SGLT) and glycogen phosphorylase (GP) inhibitors, PHARMACEUTICALS 14: (4) 364
type of document: Journal paper/Article
language: English
URL 
2019

Kaszás Tímea, Tóth Marietta, Langer Peter, Somsák László: C-Glycosyl Styrene Type Compounds by Pd-Catalyzed Cross-Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Benzyl Bromides, ADVANCED SYNTHESIS & CATALYSIS 361: (1) pp. 105-117.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2019

József János, Juhász László, Somsák László: Thio-click reaction of 2-deoxy-exo-glycals towards new glycomimetics: stereoselective synthesis of C-2-deoxy-D-glycopyranosyl compounds, NEW JOURNAL OF CHEMISTRY 43: (15) pp. 5670-5686.
type of document: Journal paper/Article
number of independent citations: 5
language: English
URL 
2019

Szabó Katalin E., Kyriakis Efthimios, Psarra Anna-Maria G., Karra Aikaterini G., Sipos Ádám, Docsa Tibor, Stravodimos George A., Katsidou Elisabeth, Skamnaki Vassiliki T., Liggri Panagiota G. V., Zographos Spyros E., Mándi Attila, Király Sándor Balázs, Kurtán Tibor, Leonidas Demetres D., Somsák László: Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography, JOURNAL OF MEDICINAL CHEMISTRY 62: (13) pp. 6116-6136.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2018

Kun S, Begum J, Kyriakis E, Stamati ECV, Barkas TA, Szennyes E, Bokor É, Szabó EK, Stravodimos GA, Sipos Á, Docsa T, Gergely P, Moffatt C, Patraskaki MS, Kokolaki MC, Gkerdi A, Skamnaki VT, Leonidas DD, Somsák L, Hayes JM: A multidisciplinary study of 3-(beta-D-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: computation, synthesis, crystallography and kinetics reveal new potent inhibitors, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 147: pp. 266-278.
type of document: Journal paper/Article
number of independent citations: 5
language: English
URL 
2017

Bokor Éva, Kun Sándor, Goyard David, Tóth Marietta, Praly Jean-Pierre, Vidal Sébastien, Somsák László: C‑Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential, CHEMICAL REVIEWS 117: (3) pp. 1687-1764.
type of document: Journal paper/Review paper
number of independent citations: 88
language: English
URL 
2008

Somsák L, Czifrák K, Tóth M, Bokor É, Chrysina E D, Alexacou K-M, Hayes J M, Tiraidis C, Lazoura E, Leonidas D D, Zographos S E, Oikonomakos N G: New inhibitors of glycogen phosphorylase as potential antidiabetic agents, CURRENT MEDICINAL CHEMISTRY 15: pp. 2933-2983.
type of document: Journal paper/Review paper
number of independent citations: 75
language: English
URL 
2003

Somsák L, Nagy V, Hadady Zs, Docsa T, Gergely P: Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments, CURRENT PHARMACEUTICAL DESIGN 9: pp. 1177-1189.
type of document: Journal paper/Article
number of independent citations: 195
language: English
URL 
2001

Somsak L, Kovacs L, Toth M, Osz E, Szilagyi L, Gyorgydeak Z, Dinya Z, Docsa T, Toth B, Gergely P: Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of D-gluco- and D-xylopyranosylidene-spiro-(thio)hydantoins and N-(D-glucopyranosyl) amides, JOURNAL OF MEDICINAL CHEMISTRY 44: pp. 2843-2848.
type of document: Journal paper/Article
number of independent citations: 122
language: English
URL 
2001

Somsak L: Carbanionic reactivity of the anomeric center in carbohydrates, CHEMICAL REVIEWS 101: (1) pp. 81-135.
type of document: Journal paper/Review paper
number of independent citations: 157
language: English
URL 
Number of independent citations to these publications:653 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
382
number of scientific publications:
384
monographs and professional books:
3
monographs/books in which chapters/sections were contributed:
10 
number of independent citations to scientific publications and creative works:
2968
further relevant information regarding accreditation (in Hungarian)
Somsák, László (Ed.) Carbohydrate-spiro-heterocycles Springer, Svájc : Springer International Publishing (2019) , 299 pp. DOI ISBN: 9783030319410 ISBN: 9783030319427 A. P. Rauter, B. E. Christensen, L. Somsák, P. Kosma, R. Adamo (Eds.): Recent Trends in Carbohydrate Chemistry, Vols. 1-2. Elsevier, Amsterdam, 2020. Vol. 1. Paperback ISBN: 9780128174678, eBook ISBN: 9780128174685 Vol 2. Paperback ISBN: 9780128209547, eBook ISBN: 9780128209554

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )