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personal data approved: 2019. IV. 14.
Personal data
name Szilvia Bősze
name of institution
doctoral school
ELTE György Hevesy Doctoral School of Chemistry (Supervisor)
accreditation statement submitted to: Eötvös Loránd University, Budapest
Contact details
phone number +36 1 372-2500/1409
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 1999
discipline to which degree belongs chemistry
institution granting the degree Eötvös Loránd Tudományegyetem (to be translated)
Employment
1991 - MTA Peptidkémiai Kutatócsoport (research institute, not university)
other (not specified) (tud. főmunkatárs)
Thesis topic supervisor
number of doctoral students supervised until now 5.5
number of students who fulfilled course requirements 3
students who obtained their degrees:
Zsuzsa Baranyai PhD 2018  DSC-ELTE
(50%) Hajnalka Szabados PhD 2016  DSC-ELTE
Kata Horváti PhD 2009  DSC-ELTE

completed course requirement, without degree or degree granting in process:
Ferenc Szakács (PhD) 2012/08  
(50%) Gergely Kohut (PhD) 2020/08  DSC-ELTE
Zsuzsa Éva Baranyai (PhD) 2014/08  DSC-ELTE
present PhD students:
Lilla Borbála Horváth (PhD) (2021/08)  DSC-ELTE
  Thesis topic proposals
Research
research area Immunodiagnosis of tuberculosis, host cell specific targeting of antituberculars, peptide chemistry, microanalysis, flow cytometry, immunochemical methods
research field in which current research is conducted biology
chemistry
Publications
2019

Gyulai Gergő, Ouanzi Fatima, Bertóti Imre, Mohai Miklós, Kolonits Tamás, Horváti Kata, Bősze Szilvia: Chemical structure and in vitro cellular uptake of luminescent carbon quantum dots prepared by solvothermal and microwave assisted techniques, JOURNAL OF COLLOID AND INTERFACE SCIENCE 549: pp. 150-161.
type of document: Journal paper/Article
language: English
URL 
2018

Horváti K, Gyulai G, Csámpai A, Rohonczy J, Kiss E, Bosze SE: Surface layer modification of PLGA nanoparticles with targeting peptide: A convenient synthetic route for Pluronic F127 - Tuftsin conjugate, BIOCONJUGATE CHEMISTRY 29: (5) pp. 1495-1499.
type of document: Journal paper/Article
language: English
URL 
2018

Kiss Éva, Gyulai Gergő, Pári Edit, Horváti Kata, Bősze Szilvia: Membrane affinity and fluorescent labelling: comparative study of monolayer interaction, cellular uptake and cytotoxicity profile of carboxyfluorescein-conjugated cationic peptides, AMINO ACIDS 50: (11) pp. 1557-1571.
type of document: Journal paper/Article
language: English
URL 
2017

Horváti Kata, Bacsa Bernadett, Mlinkó Tamás, Szabó Nóra, Hudecz Ferenc, Zsila Ferenc, Bősze Szilvia: Comparative analysis of internalisation, haemolytic, cytotoxic and antibacterial effect of membrane-active cationic peptides: aspects of experimental setup, AMINO ACIDS 49: (6) pp. 1053-1067.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2017

Baranyai Z, Kratky M, Vosatka R, Szabo E, Senoner Z, David S, Stolarikova J, Vinsova J, Bosze S: In vitro biological evaluation of new antimycobacterial salicylanilide-tuftsin conjugates., EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 133: pp. 152-173.
type of document: Journal paper/Article
language: English
URL 
2016

Ábrahám Á, Baranyai Zs, Gyulai G, Pári E, Horváti K, Bősze Sz, Kiss É: Comparative analysis of new peptide conjugates of antitubercular drug candidates − model membrane and in vitro studies, COLLOIDS AND SURFACES B: BIOINTERFACES 147: pp. 106-115.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2016

Gyulai G, Magyar A, Rohonczy J, Orosz J, Yamasaki M, Bosze Sz, Kiss É: Preparation and characterization of cationic Pluronic for surface modification and functionalization of polymeric drug delivery nanoparticles, EXPRESS POLYMER LETTERS 10: (3) pp. 216-226.
type of document: Journal paper/Article
number of independent citations: 11
language: English
URL 
2015

Zs Baranyai, M Krátký, J Vinšová, N Szabó, Zs Senoner, K Horváti, J Stolaříková, S Dávod, Sz Bősze: Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 101: pp. 692-704.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2014

Horváti Kata, Bacsa Bernadett, Kiss Éva, Gyulai Gergő, Fodor Kinga, Balka Gyula, Rusvai Miklós, Szabó Eleonóra, Hudecz Ferenc, Bősze Szilvia: Nanoparticle Encapsulated Lipopeptide Conjugate of Antitubercular Drug Isoniazid: In Vitro Intracellular Activity and in Vivo Efficacy in a Guinea Pig Model of Tuberculosis, BIOCONJUGATE CHEMISTRY 25: (12) pp. 2260-2268.
type of document: Journal paper/Article
number of independent citations: 20
language: English
URL 
2012

Horvati K, Bacsa B, Szabo N, David S, Mezo G, Grolmusz V, Vertessy BG, Hudecz F, Bosze S: Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation, BIOCONJUGATE CHEMISTRY 23: (5) pp. 900-907.
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL 
Number of independent citations to these publications:51 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
254
number of scientific publications:
244
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
1 
scientific publications published abroad that meet the accreditation criteria:
218
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
13
number of independent citations to scientific publications and creative works:
1003
further relevant information regarding accreditation (in Hungarian)
Meghívott előadások (konferencia, intézmény): 2010, Magyar Tudomány Ünnepe, A tuberkulózis terápia új megközelitési módszerei 2012, University of Zurich, Sciex-NMS, home mentor lecture, Application of Bioactive Peptides and Peptide Conjugates 2014, Charles University, Why chemists are needed? Faculty of Pharmacy, Hradec Králové, 2015, 17th International Congress of the Hungarian Society for Microbiology, meghívott előadó 2019, 11th Joint Meeting on Medicinal Chemistry, meghívott előadó (to be translated)

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )