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personal data approved: 2020. XI. 27.
Personal data
György Keserű
name György Keserű
name of institution
Budapest University of Technology and Economics
Doctoral Council of the University (external member)
doctoral school
BME George A. Olah Doctoral School of Chemistry and Chemical Technology (Core member)
(discipline) Habilitation Comittee and Doctoral Council (external member)
SE Doctoral School of Pharmaceutical Sciences (Academic staff member)
the share of work in the different doctoral schools. BME George A. Olah Doctoral School of Chemistry and Chemical Technology 60%
SE Doctoral School of Pharmaceutical Sciences 38%
BME GAODSCC (discipline) Habilitation Comittee and Doctoral Council (external member) 1%
BME Doctoral Council of the University (external member) 1%
accreditation statement submitted to: Budapest University of Technology and Economics
HAC accreditation
full compliance
(2019. III. 29.)
Contact details
E-mail address gy.keseruttk.mta.hu
phone number +36 1 382-6821
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 1994
discipline to which degree belongs chemistry
institution granting the degree HAS
scientific degree, title DSc
year degree was obtained 2003
discipline to which degree belongs
institution granting the degree HAS
Employment
2013 - MTA Természettudományi Kutatóközpont (research institute, not university)
scientific consultant
Thesis topic supervisor
number of doctoral students supervised until now 9
number of students who fulfilled course requirements 6
students who obtained their degrees:
Bence Szilágyi PhD 2020  GAODSCC
Ádám Andor Kelemen PhD 2018  GAODSCC
Dávid Bajusz PhD 2017  GAODSCC
Ákos Tarcsay PhD 2014  GAODSCC
Márton Vass PhD 2014  GAODSCC
(50%) Róbert Kiss PhD 2008  DSPS1-SE
Tímea Polgár PhD 2006  GAODSCC
György Tibor Balogh PhD 2003  GAODSCC
László Molnár PhD 2003  GAODSCC
(50%) Dóra Menyhárd PhD 1998  DSPS1-SE

students with degree granting in process:
László Petri PhD (2022/03)  GAODSCC
completed course requirement, without degree or degree granting in process:
Aaron Brian Keeley (PhD) 2020/01  GAODSCC
Andrea Scarpino (PhD) 2020/08  GAODSCC
Zoltán Orgován (PhD) 2020/08  GAODSCC
present PhD students:
Nikolett Péczka (PhD) (2024/01)  GAODSCC
Dénes Szepesi Kovács (PhD) (2023/01)  GAODSCC
Levente Kollár (PhD) (2023/01)  GAODSCC
  Thesis topic proposals
Research
research area medicinal chemistry, drug design
research field in which current research is conducted chemistry
pharmaceutics
Publications
2020

Menyhard Dora K., Palfy Gyula, Orgovan Zoltan, Vida Istvan, Keseru Gyorgy M., Perczel Andras: Structural impact of GTP binding on downstream KRAS signaling, CHEMICAL SCIENCE 11: (34) pp. 9272-9289.
type of document: Journal paper/Article
language: English
URL 
2019

Christopher John A., Orgován Zoltán, Congreve Miles, Doré Andrew S., Errey James C., Marshall Fiona H., Mason Jonathan S., Okrasa Krzysztof, Rucktooa Prakash, Serrano-Vega Maria J., Ferenczy György G., Keserű György M.: Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray Structures, JOURNAL OF MEDICINAL CHEMISTRY 62: (1) pp. 207-222.
type of document: Journal paper/Article
number of independent citations: 18
language: English
URL 
2019

Yueh Christine, Rettenmaier Justin, Xia Bing, Hall David R., Alekseenko Andrey, Porter Kathryn A., Barkovich Krister, Keseru Gyorgy, Whitty Adrian, Wells James A., Vajda Sandor, Kozakov Dima: Kinase Atlas: Druggability Analysis of Potential Allosteric Sites in Kinases, JOURNAL OF MEDICINAL CHEMISTRY 62: (14) pp. 6512-6524.
type of document: Journal paper/Article
number of independent citations: 6
language: English
URL 
2019

Wakefield Amanda E., Mason Jonathan S., Vajda Sandor, Keserű György M.: Analysis of tractable allosteric sites in G protein-coupled receptors, SCIENTIFIC REPORTS 9: (1) 6180
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2019

Egbert Megan, Whitty Adrian, Keserű György M., Vajda Sandor: Why Some Targets Benefit from beyond Rule of Five Drugs, JOURNAL OF MEDICINAL CHEMISTRY 62: (22) pp. 10005-10025.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2019

Orlova Anna, Wagner Christina, de Araujo Elvin D., Bajusz Dávid, Neubauer Heidi A., Herling Marco, Gunning Patrick T., Keserű György M., Moriggl Richard: Direct Targeting Options for STAT3 and STAT5 in Cancer, CANCERS 11: (12) p. 1930.
type of document: Journal paper/Review paper
number of independent citations: 10
language: English
URL 
2018

Wingelhofer Bettina, Maurer Barbara, Heyes Elizabeth C, Cumaraswamy Abbarna C, Berger-Becvar Angelika, de Araujo Elvin D, Orlova Anna, Freund Patricia, Ruge Frank, Park Jisung, Tin Gary, Ahmar Siawash, Lardeau Charles-Hugues, Sadovnik Irina, Bajusz Dávid, Keserű György Miklós, Grebien Florian, Kubicek Stefan, Valent Peter, Gunning Patrick T, Moriggl Richard: Pharmacologic inhibition of STAT5 in acute myeloid leukemia, LEUKEMIA 32: (5) pp. 1135-1146.
type of document: Journal paper/Article
number of independent citations: 34
language: English
URL 
2018

Orlova Anna, Wingelhofer Bettina, Neubauer Heidi A, Maurer Barbara, Berger-Becvar Angelika, Keserű György Miklós, Gunning Patrick T, Valent Peter, Moriggl Richard: Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas, EXPERT OPINION ON THERAPEUTIC TARGETS 22: (1) pp. 45-57.
type of document: Journal paper/Review paper
number of independent citations: 4
language: English
URL 
2018

Scarpino A, Ferenczy GG, Keserü GM: Comparative Evaluation of Covalent Docking Tools, JOURNAL OF CHEMICAL INFORMATION AND MODELING 58: (7) pp. 1441-1458.
type of document: Journal paper/Article
number of independent citations: 21
language: English
URL 
2018

Boström J., Brown D.G., Young R.J., Keserü G.M.: Expanding the medicinal chemistry synthetic toolbox, NATURE REVIEWS DRUG DISCOVERY 17: (10) pp. 709-727.
type of document: Journal paper/Article
number of independent citations: 79
language: English
URL 
Number of independent citations to these publications:179 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
304
number of scientific publications:
307
monographs and professional books:
4
monographs/books in which chapters/sections were contributed:
12 
number of independent citations to scientific publications and creative works:
4965
further relevant information regarding accreditation (in Hungarian)
egyetemi magántanár (2004-től) a Budapesti Műszaki és Gazdaságtudományi Egyetem Vegyészmérnöki és Biomérnöki Karán Molekulatervezés illetve Molekulamodellezés tantárgyak oktatása a Budapesti Műszaki és Gazdaságtudományi Egyetemen 1993-től minden szemeszterben Gyógyszertervezés tantárgy oktatása Budapesti Műszaki és Gazdaságtudományi Egyetemen, az Eötvös Loránd Tudományegyetemen, a Debreceni Egyetemen és a Pécsi Egyetemen 2010-től (to be translated)

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )