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personal data approved: 2019. IV. 15.
Personal data
name Ervin Welker
name of institution
doctoral school
BME George A. Olah Doctoral School of Chemistry and Chemical Technology (Academic staff member)
ELTE Doctoral School of Biology (Academic staff member)
SE Doctoral School of Molecular Medicine (Supervisor)
SzTE Doctoral School of Multidisciplinary Medical Scienses (Supervisor)
SzTE Doctoral School of Biology (Academic staff member)
the share of work in the different doctoral schools. ELTE Doctoral School of Biology 20%
SzTE Doctoral School of Multidisciplinary Medical Scienses 80%
accreditation statement submitted to: University of Szeged
Contact details
E-mail address welkerbrc.hu
phone number +36 30 415-8500
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 1997
discipline to which degree belongs biology
institution granting the degree ELTE (to be translated)
scientific degree, title DSc
year degree was obtained 2008
discipline to which degree belongs biology
institution granting the degree HAS
Employment
2012 - Természettudományi Kutatóközpont (research institute, not university)
scientific consultant
2004 - Szegedi Biologiai Kutató Intézet (research institute, not university)
2004 - Szegedi Biologiai Kutató Intézet (research institute, not university)
scientific consultant
Thesis topic supervisor
number of doctoral students supervised until now 4
number of students who fulfilled course requirements 1
students who obtained their degrees:
Antal Nyeste PhD 2016  DSMMS
(50%) Pradeep Kumar Reddy Cingaram PhD 2016  USz-DSB
(50%) Eszter Tóth PhD 2015  DSB-ELTE

students with degree granting in process:
(50%) Babu Sangeetham Sudheer PhD (2019/12)  DSMMS
Péter István Kulcsár PhD (2019/12)  DSMMS
completed course requirement, without degree or degree granting in process:
Krisztina Huszár (PhD) 2012/08  
Nóra Weinhardt (PhD) 2018/08  USz-DSB
present PhD students:
Éva Varga (PhD) (2022/08)  DSMMS
Sarah Laura Krausz (PhD) (2020/08)  DSMM-SE
Zoltán Mihály Ligeti (PhD) (2019/08)  DSMMS
hiányos adatú hallgatói:
András Tálas PhD (2017/08)  DSMM-SE
  Thesis topic proposals
Research
research area We are interested in developing CRISPR/Cas-based genome engineering methodologies and generating disease models and genetically modified entities in different animal/cell systems.
research field in which current research is conducted biology
Publications
2018

Tóth Eszter, Czene Bernadett C, Kulcsár Péter I, Krausz Sarah L, Tálas András, Nyeste Antal, Varga Éva, Huszár Krisztina, Weinhardt Nóra, Ligeti Zoltán, Borsy Adrienn É, Fodor Elfrieda, Welker Ervin: Mb- and FnCpf1 nucleases are active in mammalian cells, NUCLEIC ACIDS RESEARCH 46: (19) pp. 10272-10285.
type of document: Journal paper/Article
language: English
URL 
2017

Tálas András, Péter Istvan Kulcsár, Nóra Weinhardt, Adrienn Borsy, Eszter Tóth, Kornélia Szebényi, Sarah Laura Krausz, Krisztina Huszár, István Vida, Ádám Sturm, Bianka Gordos, Orsolya Ivett Hoffmann, Petra Bencsura, Antal Nyeste, Zoltán Ligeti, Elfrieda Fodor, Ervin Welker: A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid., DNA RESEARCH 24: (6) pp. 609-621.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2017

Kulcsar PI, Talas A, Huszar K, Ligeti Z, Toth E, Weinhardt N, Fodor E, Welker E: Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage., GENOME BIOLOGY 18: 190
type of document: Journal paper/Article
number of independent citations: 12
language: English
URL 
2016

Nyeste A, Bencsura P, Vida I, Hegyi Z, Homolya L, Fodor E, Welker E: Expression of the prion protein family member Shadoo causes drug hypersensitivity that is diminished by the coexpression of the wild type prion protein., JOURNAL OF BIOLOGICAL CHEMISTRY 291: (9) pp. 4473-4486.
type of document: Journal paper/Article
language: English
URL 
2016

Toth E, Weinhardt N, Bencsura P, Huszar K, Kulcsar PI, Talas A, Fodor E, Welker E: Cpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells, BIOLOGY DIRECT 11: 46
type of document: Journal paper/Article
number of independent citations: 21
language: English
URL 
2008

Narayan M, Welker E, Zhai H, Han X, Xu G, McLafferty FW, Scheraga HA: Detecting native folds in mixtures of proteins that contain disulfide bonds, NATURE BIOTECHNOLOGY 26: pp. 427-429.
type of document: Journal paper/Article
number of independent citations: 7
language: English
URL 
2002

Welker E, Raymond LD, Scheraga HA, Caughey B: Intramolecular versus intermolecular disulfide bonds in prion proteins, JOURNAL OF BIOLOGICAL CHEMISTRY 277: pp. 33477-33481.
type of document: Journal paper/Article
number of independent citations: 60
language: English
URL 
2001

Welker E, Narayan M, Wedemeyer WJ, Scheraga HA: Structural determinants of oxidative folding in proteins, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98: pp. 2312-2316.
type of document: Journal paper/Article
number of independent citations: 53
language: English
URL 
2001

Welker E, Wedemeyer WJ, Scheraga HA: A role for intermolecular disulfide bonds in prion diseases?, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98: pp. 4334-4336.
type of document: Journal paper/Article
number of independent citations: 50
language: English
URL 
2000

WEDEMEYER WJ, WELKER E, NARAYAN M, SCHERAGA HA: Disulfide bonds and protein folding, BIOCHEMISTRY 39: pp. 4207-4216.
type of document: Journal paper/Article
number of independent citations: 328
language: English
DOI 
Number of independent citations to these publications:535 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
50
number of scientific publications:
52
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
1842

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )