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personal data approved: 2024. II. 17.
Personal data
Attila Paczal
name Attila Paczal
name of institution
doctoral school
BME George A. Olah Doctoral School of Chemistry and Chemical Technology (Academic staff member)
ELTE György Hevesy Doctoral School of Chemistry (Supervisor)
PTE Doctoral School of Chemistry (Academic staff member)
the share of work in the different doctoral schools. BME George A. Olah Doctoral School of Chemistry and Chemical Technology 5%
ELTE György Hevesy Doctoral School of Chemistry 90%
PTE Doctoral School of Chemistry 5%
accreditation statement submitted to: Eötvös Loránd University, Budapest
Contact details
E-mail address attila.paczalservier.com
Academic title
scientific degree, title Ph.D.
year degree was obtained 2008
discipline to which degree belongs chemistry
institution granting the degree Eötvös Loránd University (ELTE)
Employment
2008 - SERVIER GYÓGYSZERKUTATÓ INTÉZET ZRT.
other (not specified) (Senior Kutató)
Thesis topic supervisor
number of doctoral students supervised until now 1.5
number of students who fulfilled course requirements 0.5
students who obtained their degrees:
(50%) Zita Petró-Szabó PhD 2022  DSC-PTE

completed course requirement:
(50%) Zita Petró-Szabó (PhD) 2022/08  DSC-PTE
present PhD students:
(50%) Gréta Galgóczy (PhD) (2026/08)  DSC-ELTE
  Thesis topic proposals
Research
research area Organic and organometallic chemistry; Medicinal chemistry: inhibition of protein-protein interactions, targeted active drug intake (ADC, PROTAC); Synthesis and application of chiral carbene ligands.
research field in which current research is conducted chemistry
pharmaceutics
Publications
2022

Zita Szabó, Attila Paczal, Tibor Kovács, Attila Mándi, Andras Kotschy, Tibor Kurtán: Synthesis and Vibrational Circular Dichroism Analysis of N-Heterocyclic Carbene Precursors Containing Remote Chirality Centers, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23: (7) p. 1.
type of document: Journal paper/Article
language: English
URL 
2022

Zita Szabo, Sophia Ben Ahmed, Zoltan Nagy, Attila Paczal, Andras Kotschy: Enantioselective Cyclopropanation Catalyzed by Gold(I)-Carbene Complexes, MOLECULES 27: (5805) https://doi.org/10.3390/molecules27185805
type of document: Journal paper/Article
language: English
URL 
2021

Csaba Weber, Melinda Sipos, Attila Paczal, Balazs Balint, Vilibald Kun, Nicolas Foloppe, Pawel Dokurno, Andrew J. Massey, Thomas Edmonds, Didier Demarles, Alain Bruno, Mike Burbridge, Francisco Cruzalegui, Andras Kotschy: Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors, JOURNAL OF MEDICINAL CHEMISTRY 64: pp. 6745-6764.
type of document: Journal paper/Article
language: English
URL 
2020

Sinai Ádám, Simkó Dániel Csaba, Szabó Fruzsina, Paczal Attila, Gati Tamas, Benyei Attila, Novák Zoltán, Kotschy András: Aryl-Diadamantyl Phosphine Ligands in Palladium-Catalyzed Cross-Coupling Reactions: Synthesis, Structural Analysis, and Application, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2020: (9) pp. 1122-1128.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2020

Szabo Zita, Timari Matyas, Kassai Rudolf, Szokol Bianka, Benyei Attila C., Gáti Tamás, Paczal Attila, Kotschy Andras: Modular Synthesis of Chiral NHC Precursors and Their Silver and Gold Complexes, ORGANOMETALLICS 39: (19) pp. 3572-3589.
type of document: Journal paper/Article
language: English
URL 
2020

Szlavik Zoltan, Csekei Marton, Paczal Attila, Szabo Zoltan B., Sipos Szabolcs, Radics Gabor, Proszenyak Agnes, Balint Balazs, Murray James, Davidson James, Chen Ijen, Dokurno Pawel, Surgenor Allan E, Daniels Zoe Marie, Hubbard Roderick E., Le Toumelin-Braizat Gaëtane, Claperon Audrey, Lysiak-Auvity Gaëlle, Girard Anne-Marie, Bruno Alain, Chanrion Maia, Colland Frédéric, Maragno Ana-Leticia, Demarles Didier, Geneste Olivier, Kotschy Andras: Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor, JOURNAL OF MEDICINAL CHEMISTRY 63: (22) pp. 13762-13795.
type of document: Journal paper/Article
number of independent citations: 10
language: English
URL 
2019

Szlávik Zoltan, Ondi Levente, Csékei Márton, Paczal Attila, Szabó Zoltán B., Radics Gábor, Murray James, Davidson James, Chen Ijen, Davis Ben, Hubbard Roderick E., Pedder Christopher, Dokurno Pawel, Surgenor Allan, Smith Julia, Robertson Alan, LeToumelin-Braizat Gaetane, Cauquil Nicolas, Zarka Marion, Demarles Didier, Perron-Sierra Francoise, Claperon Audrey, Colland Frederic, Geneste Olivier, Kotschy András: Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity, JOURNAL OF MEDICINAL CHEMISTRY 62: (15) pp. 6913-6924.
type of document: Journal paper/Article
number of independent citations: 21
language: English
URL 
2016

Paczal Attila, Bálint Balázs, Wéber Csaba, Szabó Zoltán B, Ondi Levente, Isabelle Theret, Frédéric De Ceuninck, Catherine Bernard, Alain Ktorza, Francoise Perron-Sierra, Kotschy András: Structure–Activity Relationship of Azaindole-Based Glucokinase Activators, JOURNAL OF MEDICINAL CHEMISTRY 59: (2) pp. 687-706.
type of document: Journal paper/Article
number of independent citations: 12
language: English
URL 
2016

Kotschy András, Szlavik Zoltán, James Murray, James Davidson, Ana Leticia Maragno, Gaëtane Le Toumelin-Braizat, Maïa Chanrion, Gemma L Kelly, Jia-Nan Gong, Donia M Moujalled, Alain Bruno, Csekei Márton, Paczal Attila, Szabo B Zoltán, Sipos Szabolcs, Radics Gábor, Proszenyak Agnes, Balint Balázs, Ondi Levente, Blasko Gábor, Alan Robertson, Allan Surgenor, Pawel Dokurno, Ijen Chen, Natalia Matassova, Julia Smith, Christopher Pedder, Christopher Graham, Aurélie Studeny, Gaëlle Lysiak-Auvity, Anne-Marie Girard, Fabienne Gravé, David Segal, Chris D Riffkin, Giovanna Pomilio, Laura C A Galbraith, Brandon J Aubrey, Margs S Brennan, Marco J Herold, Catherine Chang, Ghislaine Guasconi, Nicolas Cauquil, Fabien Melchiore, Nolwen Guigal-Stephan, Brian Lockhart, Frédéric Colland, John A Hickman, Andrew W Roberts, David C S Huang, Andrew H Wei, Andreas Strasser, Guillaume Lessene, Olivier Geneste: The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models, NATURE 538: (7626) pp. 477-482.
type of document:
number of independent citations: 506
language: English
URL 
2006

Paczal A, Benyei AC, Kotschy A: Modular synthesis of heterocyclic carbene precursors, JOURNAL OF ORGANIC CHEMISTRY 71: (16) pp. 5969-5979.
type of document: Journal paper/Article
number of independent citations: 86
language: English
URL 
Number of independent citations to these publications:636 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
19
number of scientific publications:
19
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
926


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )