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personal data approved: 2016. XI. 27.
Personal data
Lajos Széles
name Lajos Széles
year of birth 1971
name of institution
doctoral school
DE Doctoral School of Molecular Cellular and Immune Biology (Supervisor)
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address szeleslmed.unideb.hu
phone number +36 52 411-717
Academic title
scientific degree, title Ph.D.
year degree was obtained 2009
discipline to which degree belongs theoretical medicine
institution granting the degree University of Debrecen
Employment
2015 - University of Debrecen
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now
number of students who fulfilled course requirements
students who obtained their degrees:
present PhD students:
Mária Csumita (PhD) (2019/08)  DSMCI
  Thesis topic proposals
Research
research area Transcriptional regulation of immune responses
research field in which current research is conducted theoretical medicine
biology
Publications
2015

Szeles Lajos, Meissner Felix, Dunand-Sauthier Isabelle, Thelemann Christoph, Hersch Micha, Singovski Simon, Haller Sergio, Gobet Florian, Marraco Silvia A Fuertes, Mann Matthias, Garcin Dominique, Acha-Orbea Hans, Reith Walter: TLR3-Mediated CD8(+) Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State, JOURNAL OF IMMUNOLOGY 195: (3) pp. 1025-1033.
type of document: Journal paper/Article
language: English
DOI 
2013

Gyongyosi A, Szatmari I, Pap A, Dezso B, Pos Z, Szeles L, Varga T, Nagy L: RDH10, RALDH2 and CRABP2 are required components of PPARg-directed all-trans-retinoic acid synthesis and signaling in human dendritic cells, JOURNAL OF LIPID RESEARCH 54: (9) pp. 2458-2474. pp. 2458-2474.
type of document: Journal paper/Article
number of independent citations: 6
language: English
URL 
2012

Nagy L, Szanto A, Szatmari I, Széles L: Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response, PHYSIOLOGICAL REVIEWS 92: (2) pp. 739-789.
type of document: Journal paper/Review paper
number of independent citations: 57
language: English
DOI 
2011

Poliska S, Csanky E, Szanto A, Szatmari I, Mesko B, Szeles L, Dezso B, Scholtz B, Podani J, Kilty I, Takacs L, Nagy L: COPD-specific gene expression signatures of alveolar macrophages and also peripheral blood monocytes overlap and correlate with lung function, RESPIRATION 81: (6) pp. 499-510.
type of document: Journal paper/Article
number of independent citations: 18
language: English
URL 
2011

Nakken B, Varga T, Szatmari I, Szeles L, Gyongyosi A, Illarionov P, Dezso B, Gogolak P, Rajnavolgyi E, Nagy L: Peroxisome Proliferator-Activated Receptor gamma-Regulated Cathepsin D Is Required for Lipid Antigen Presentation by Dendritic Cells, JOURNAL OF IMMUNOLOGY 187: (1) pp. 240-247.
type of document: Journal paper/Article
number of independent citations: 9
language: English
URL 
2010

Szeles L, Poliska S, Nagy G, Szatmari I, Szanto A, Pap A, Lindstedt M, Santegoets SJAM, Ruhl R, Dezso B, Nagy L: Research Resource: Transcriptome Profiling of Genes Regulated by RXR and Its Permissive and Nonpermissive Partners in Differentiating Monocyte-Derived Dendritic Cells, MOLECULAR ENDOCRINOLOGY 24: (11) pp. 2218-2231.
type of document: Journal paper/Article
number of independent citations: 24
language: English
URL 
2010

Szanto A, Balint L B, Nagy Z, Barta E, Dezso B, Pap A, Szeles L, Poliska S, Oros M, Evans R M, Barak Y, Schwabe J, Nagy L: STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells, IMMUNITY 33: (5) pp. 699-712.
type of document: Journal paper/Article
number of independent citations: 97
language: English
URL 
2009

Széles L, Keresztes G, Törőcsik D, Balajthy Z, Krenács L, Póliska Sz, Steinmeyer A, Zuegel A, Pruenster M, Rot A, Nagy L: 1,25-dihydroxyvitaminD3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype, JOURNAL OF IMMUNOLOGY 182: (4) pp. 2074-2083.
type of document: Journal paper/Article
number of independent citations: 91
language: English
DOI 
2007

Szeles L, Torocsik D, Nagy L: PPARgamma in immunity and inflammation: cell types and diseases, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1771: (8) pp. 1014-1030.
type of document: Journal paper/Article
number of independent citations: 78
language: English
DOI 
2006

Szatmari I, Vámosi G, Brazda P, Balint LB, Benko S, Széles L, Jeney V, Özvegy-Laczka G, Szántó A, Barta E, Balla J, Sarkadi B, Nagy L: PPARg reguleted ABCG2 expression confers cytoprotection to human dendritic cells, JOURNAL OF BIOLOGICAL CHEMISTRY 281: (33) pp. 23812-23823.
type of document: Journal paper/Article
number of independent citations: 110
language: English
DOI 
Number of independent citations to these publications:490 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
14
number of scientific publications:
14
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
618

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )