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personal data approved: 2022. VIII. 04.
Personal data
Tibor Docsa
name Tibor Docsa
name of institution
doctoral school
DE Doctoral School of Molecular Medicine (Supervisor)
the share of work in the different doctoral schools. DE Doctoral School of Molecular Medicine 100%
accreditation statement submitted to: University of Debrecen
Contact details
E-mail address tdocsamed.unideb.hu
phone number +36 52 412-345/61192
Academic title
scientific degree, title Ph.D.
year degree was obtained 2013
discipline to which degree belongs theoretical medicine
institution granting the degree University of Debrecen
Employment
2013 - University of Debrecen
other (not specified) (adjunktus)
Thesis topic supervisor
number of doctoral students supervised until now
number of students who fulfilled course requirements
students who obtained their degrees:
Ádám Sipos PhD 2022  DSMM-UD

present PhD students:
Luca Anna Fodor-Varga (PhD) (2026/08)  DSMM-UD
  Thesis topic proposals
Research
research area Identify the effect of glycogen phosphorylase inhibitors on the glycogen metabolism in diabetic animal models and cell systems.
research field in which current research is conducted theoretical medicine
Publications
2021

Sipos Á, Szennyes E, Hajnal ÉN, Kun S, Szabó KE, Uray K, Somsák L, Docsa T, Bokor É: Dual-target compounds against type 2 Diabetes Mellitus: proof of concept for sodium dependent glucose transporter (SGLT) and glycogen phosphorylase (GP) inhibitors, PHARMACEUTICALS 14: (4) 364
type of document: Journal paper/Article
language: English
URL 
2020

Docsa Tibor, Bhattarai Deepa, Sipos Adam, Wade Charles E., Cox Charles S., Uray Karen: CXCL1 is upregulated during the development of ileus resulting in decreased intestinal contractile activity, NEUROGASTROENTEROLOGY AND MOTILITY 32: pp. 1-12.
type of document: Journal paper/Article
language: English
URL 
2020

Goyard David, Kónya Bálint, Czifrák Katalin, Larini Paolo, Demontrond Fanny, Leroy Jérémy, Balzarin Sophie, Tournier Michel, Tousch Didier, Petit Pierre, Duret Cédric, Maurel Patrick, Docsa Tibor, Gergely Pál, Somsák László, Praly Jean-Pierre, Azay-Milhau Jacqueline, Vidal Sébastien: Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition, ORGANIC & BIOMOLECULAR CHEMISTRY 18: (5) pp. 931-940.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2019

Barr Daniel, Szennyes Eszter, Bokor Éva, Al-Oanzi Ziad H., Moffatt Colin, Kun Sándor, Docsa Tibor, Sipos Ádám, Davies Matthew P., Mathomes Rachel T., Snape Timothy J., Agius Loranne, Somsák László, Hayes Joseph M.: Identification of C -β- d -Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies, ACS CHEMICAL BIOLOGY 14: (7) pp. 1460-1470.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2018

Nagy L, Márton J, Vida A, Kis G, Bokor É, Kun S, Gönczi M, Docsa T, Tóth A, Antal M, Gergely P, Csóka B, Pacher P, Somsák L, Bai P: Glycogen phosphorylase inhibition improves β-cell function, BRITISH JOURNAL OF PHARMACOLOGY 175: (2) pp. 301-319.
type of document: Journal paper/Article
number of independent citations: 11
language: English
URL 
2016

Kantsadi AL, Bokor É, Kun S, Stavodimos GA, Chatzileontiadou DSM, Leonidas DD, Juhász-Tóth É, Szakács A, Batta Gy, Docsa T, Gergely P, Somsák L: Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-D-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 123: pp. 737-745.
type of document: Journal paper/Article
number of independent citations: 15
language: English
URL 
2015

Docsa T, Marics B, Németh J, Hüse Cs, Somsák L, Gergely P, Peitl B: Insulin sensitivity is modified by a glycogen phosphorylase inhibitor: glucopyranosylidene-spiro-thiohydantoin in streptozotocin-induced diabetic rats, CURRENT TOPICS IN MEDICINAL CHEMISTRY 15: pp. 2390-2394.
type of document: Journal paper/Article
number of independent citations: 11
language: English
URL 
2013

Nagy L, Docsa T, Brunyánszki A, Szántó M, Hegedűs Cs, Márton J, Kónya B, Virág L, Somsák L, Gergely P, Bai P: Glycogen phosphorylase inhibitor N-(3,5-dimethyl-benzoyl)-N'-(β-Dglucopyranosyl) urea improves glucose tolerance under normoglycemic and diabetic conditions and rearranges hepatic metabolism, PLOS ONE 8: (7) e69420
type of document: Journal paper/Article
number of independent citations: 20
language: English
URL 
2013

Bokor Éva, Docsa Tibor, Gergely Pál, Somsák László: C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase, ACS MEDICINAL CHEMISTRY LETTERS 4: (7) pp. 612-615.
type of document: Journal paper/Article
number of independent citations: 22
language: English
URL 
2011

Docsa T, Czifrák K, Hüse Cs, Somsák L, Gergely P: Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats, MOLECULAR MEDICINE REPORTS 4: (3) pp. 477-481.
type of document: Journal paper/Article
number of independent citations: 23
language: English
URL 
Number of independent citations to these publications:107 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
72
number of scientific publications:
72
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
1319

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )