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personal data approved: 2020. VIII. 03.
Personal data
Zoltán Wiener
name Zoltán Wiener
name of institution
doctoral school
SE Doctoral School of Molecular Medicine (Supervisor)
Contact details
E-mail address wiener.zoltanmed.semmelweis-univ.hu
phone number +36 1 210-2930/56432
own web page
Academic title
scientific degree, title Ph.D.
year degree was obtained 2005
discipline to which degree belongs theoretical medicine
institution granting the degree Semmelweis University, School of PhD Studies
Employment
2003 - Semmelweis University, Budapest
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 4.5
number of students who fulfilled course requirements 1.5
students who obtained their degrees:
(50%) Ádám Oszvald PhD 2021  DSMM-SE
Zsuzsanna Szvicsek PhD 2021  DSMM-SE

present PhD students:
András Áron Soós (PhD) (2023/08)  DSMM-SE
Andrea Kelemen (PhD) (2022/08)  DSMM-SE
Gyöngyvér Orsolya Sándor (PhD) (2021/08)  DSMM-SE
  Thesis topic proposals
Research
research area In our studies, we focus on the paracrine communication between tumor cells and the stroma in colorectal and pancreatic cancer models, including organoid cultures and the CRISPR-Cas9 technology.
research field in which current research is conducted theoretical medicine
biology
Publications
2020

Oszvald Ádám, Szvicsek Zsuzsanna, Sándor Gyöngyvér Orsolya, Kelemen Andrea, Soós András Áron, Pálóczi Krisztina, Bursics Attila, Dede Kristóf, Tölgyes Tamás, Buzás Edit I, Zeöld Anikó, Wiener Zoltán: Extracellular vesicles transmit epithelial growth factor activity in the intestinal stem cell niche., STEM CELLS 38: (2) pp. 291-300.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2020

Oszvald Ádám, Szvicsek Zsuzsanna, Pápai Márton, Kelemen Andrea, Varga Zoltán, Tölgyes Tamás, Dede Kristóf, Bursics Attila, Buzás Edit Irén, Wiener Zoltán: Fibroblast-derived extracellular vesicles induce colorectal cancer progression by transmitting amphiregulin, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 8: 558
type of document: Journal paper/Article
language: English
2019

Szvicsek Zsuzsanna, Oszvald Ádám, Szabó Lili, Sándor Gyöngyvér Orsolya, Kelemen Andrea, Soós András Áron, Pálóczi Krisztina, Harsányi László, Tölgyes Tamás, Dede Kristóf, Bursics Attila, Buzás Edit I., Zeöld Anikó, Wiener Zoltán: Extracellular vesicle release from intestinal organoids is modulated by Apc mutation and other colorectal cancer progression factors, CELLULAR AND MOLECULAR LIFE SCIENCES 76: (12) pp. 2463-2476.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2018

Högström Jenny, Heino Sarika, Kallio Pauliina, Lähde Marianne, Leppänen Veli-Matti, Balboa Diego, Wiener Zoltán, Alitalo Kari: Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells, CANCER RESEARCH 78: (20) pp. 5820-5832.
type of document: Journal paper/Article
number of independent citations: 4
language: English
URL 
2016

Kivelä R, Salmela I, Nguyen YH, Petrova TV, Koistinen HA, Wiener Z, Alitalo K: The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation, NATURE COMMUNICATIONS 7: 13124
type of document: Journal paper/Article
number of independent citations: 13
language: English
URL 
2016

Sodar BW, Kittel A, Paloczi K, Vukman KV, Osteikoetxea X, Szabo-Taylor K, Nemeth A, Sperlagh B, Baranyai T, Giricz Z, Wiener Z, Turiak L, Drahos L, Pallinger E, Vekey K, Ferdinandy P, Falus A, Buzas EI: Low-density lipoprotein mimics blood plasma-derived exosomes and microvesicles during isolation and detection, SCIENTIFIC REPORTS 6: 24316
type of document: Journal paper/Article
number of independent citations: 132
language: English
URL 
2014

Wiener Z, Hogstrom J, Hyvonen V, Band AM, Kallio P, Holopainen T, Dufva O, Haglund C, Kruuna O, Oliver G, Ben-Neriah Y, Alitalo K: Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance., CELL REPORTS 8: (6) pp. 1943-1956.
type of document: Journal paper/Article
number of independent citations: 25
language: English
URL 
2014

Wiener Z, Band AM, Kallio P, Hogstrom J, Hyvonen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K: Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111: (21) pp. E2229-E2236.
type of document: Journal paper/Article
number of independent citations: 27
language: English
URL 
2013

Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y: A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism, CANCER CELL 24: (2) pp. 242-256.
type of document: Journal paper/Article
number of independent citations: 88
language: English
URL 
2011

Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y: CKIalpha ablation highlights a critical role for p53 in invasiveness control., NATURE 470: (7334) pp. 409-413.
type of document: Journal paper/Article
number of independent citations: 98
language: English
URL 
Number of independent citations to these publications:393 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
38
number of scientific publications:
39
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
0 
number of independent citations to scientific publications and creative works:
2140

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )