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personal data approved: 2021. II. 18.
Personal data
Gábor Pál
name Gábor Pál
name of institution
doctoral school
ELTE Doctoral School of Biology (Core member)
accreditation statement submitted to: Eötvös Loránd University, Budapest
Contact details
phone number +36 1 372-2500/8577
Academic title
scientific degree, title Ph.D.
year degree was obtained 1997
discipline to which degree belongs biology
institution granting the degree Eötvös Loránd Tudományegyetem (to be translated)
Employment
1990 - Eötvös Loránd University, Budapest
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 8.5
number of students who fulfilled course requirements 7.5
students who obtained their degrees:
Dávid Szakács PhD 2020  DSB-ELTE
Eszter Boros PhD 2019  DSB-ELTE
(50%) Bence Kiss PhD 2015  DSB-ELTE
(50%) Áron Szenes PhD 2013  DSB-ELTE
Dávid Héja PhD 2013  DSB-ELTE
(50%) Péter Rapali PhD 2013  DSB-ELTE
(50%) Andrea Párisné Kocsis PhD 2012  
(50%) Borbála Szenthe PhD 2008  

completed course requirement:
Zoltán Attila Nagy (PhD) 2020/08  DSB-ELTE
Zoltán Bálint Németh (PhD) 2021/08  DSB-ELTE
  Thesis topic proposals
Research
research area Studying fundamental rules underlying affinity and specificity of vital protein-protein interactions using molecular biology, kinetic and directed evolution methods.
research field in which current research is conducted biology
Publications
2021

Haddad George, Lorenzen Johan M, Ma Hong, de Haan Noortje, Seeger Harald, Zaghrini Christelle, Brandt Simone, Kölling Malte, Wegmann Urs, Kiss Bence, Pál Gábor, Gál Péter, Wuthrich Rudolf P, Wuhrer Manfred, Beck Laurence H, Salant David J, Lambeau Gérard, Kistler Andreas D: Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PL A2R1-associated membranous nephropathy, JOURNAL OF CLINICAL INVESTIGATION 131: (5) e140453
type of document: Journal paper/Article
number of independent citations: 10
language: English
URL 
2019

Szakács Dávid, Kocsis Andrea, Szász Róbert, Gál Péter, Pál Gábor: Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors, JOURNAL OF BIOLOGICAL CHEMISTRY 294: (20) pp. 8227-8237.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2019

Jenny Lorenz, Noser Danilo, Larsen Julie Brogaard, Dobó József, Gál Péter, Pál Gábor, Schroeder Verena: MASP-1 of the complement system alters fibrinolytic behaviour of blood clots, MOLECULAR IMMUNOLOGY 114: pp. 1-9.
type of document: Journal paper/Article
number of independent citations: 3
language: English
URL 
2019

Nagy Zoltán Attila, Szakács Dávid, Boros Eszter, Héja Dávid, Vígh Eszter, Sándor Noémi, Józsi Mihály, Oroszlán Gábor, Dobó József, Gál Péter, Pál Gábor: Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum., PLOS PATHOGENS 15: (12) e1008232
type of document: Journal paper/Article
number of independent citations: 8
language: English
URL 
2019

Boros Eszter, Sebák Fanni, Héja Dávid, Szakács Dávid, Zboray Katalin, Schlosser Gitta, Micsonai András, Kardos József, Bodor Andrea, Pal Gabor: Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model, JOURNAL OF MOLECULAR BIOLOGY 431: (3) pp. 557-575.
type of document: Journal paper/Article
number of independent citations: 2
language: English
URL 
2016

Dobó József, Szakács Dávid, Oroszlán Gábor, Kortvely Elod, Kiss Bence, Boros Eszter, Szász Róbert, Závodszky Péter, Gál Péter, Pál Gábor: MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked, SCIENTIFIC REPORTS 6: 31877
type of document: Journal paper/Article
number of independent citations: 51
language: English
URL 
2012

Dávid Héja, Andrea Kocsis, József Dobó, Katalin Szilágyi, Róbert Szász, Péter Závodszky, Gábor Pál, Péter Gál: Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109: (26) pp. 10498-10503.
type of document: Journal paper/Article
number of independent citations: 106
language: English
URL 
2010

Kocsis A, Kékesi KA, Szász R, Végh BM, Balczer J, Dobó J, Závodszky P, Gál P, Pál G: Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation., JOURNAL OF IMMUNOLOGY 185: (7) pp. 4169-4178.
type of document: Journal paper/Article
number of independent citations: 45
language: English
URL 
2006

Pal G, Kouadio JLK, Artis DR, Kossiakoff AA, Sidhu SS: Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning, JOURNAL OF BIOLOGICAL CHEMISTRY 281: pp. 22378-22385.
type of document: Journal paper/Article
number of independent citations: 74
language: English
URL 
1998

Varallyay E, Pal G, Patthy A, Szilagyi L, Graf L: Two mutations in rat trypsin confer resistance against autolysis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 243: pp. 56-60.
type of document: Journal paper/Article
number of independent citations: 88
language: English
URL 
Number of independent citations to these publications:389 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
99
number of scientific publications:
100
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
3 
scientific publications published abroad that meet the accreditation criteria:
85
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
4
number of independent citations to scientific publications and creative works:
1205
further relevant information regarding accreditation (in Hungarian)
Tárgyfelelős illetve oktató: Biokémia 1EA; Biokémia és molekuláris biológia EA és GY; Irányított evolúciós megközelítések a fehérjetudományban EA. Jelenleg 3 PhD hallgató irányítása, eddig 8 PhD dolgozat és 12 nyertes TDK dolgozat témavezetője (6 kari és 1 országos első helyezés). ELTE TTK Kiváló Oktatója (2010), Magyar Kutatási Díj (2010), ELTE Innovatív Kutatója (2012 és 2017), Bolyai plakett (2012). Juhász-Nagy Pál Tehetséggondozó Díj (2013), Mestertanár Aranyérem Díj (2019). (to be translated)

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )