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personal data approved: 2018. IV. 25.
Personal data
Lajos László
name Lajos László
name of institution
doctoral school
ELTE Doctoral School of Biology (Supervisor)
accreditation statement submitted to: Eötvös Loránd University, Budapest
Contact details
E-mail address laszloelte.hu
phone number +36 1 372-2700/8641
Academic title
scientific degree, title CSc
year degree was obtained 1994
discipline to which degree belongs biology
institution granting the degree HAS
Employment
1980 - Eötvös Loránd University, Budapest
university professor or researcher
Thesis topic supervisor
number of doctoral students supervised until now 7.5
number of students who fulfilled course requirements 6.5
students who obtained their degrees:
(50%) Eszter Tóth PhD 2015  
(50%) Eszter Tóth PhD 2015  DSB-ELTE
Abigél Gonda PhD 2011  
Csaba Ádori PhD 2008  DSB-ELTE
Bernadett Kalmár PhD 2002  
(50%) Gábor Géza Kovács PhD 2002  
József Nagy PhD 2000  

completed course requirement, without degree or degree granting in process:
Gina Puska (PhD) 2015/08  DSB-ELTE
Gergő Botond (PhD) 2013/08  
present PhD students:
(50%) Bálint Jezsó (PhD) (2022/08)  DSB-ELTE
  Thesis topic proposals
Research
research area The role of i.) endosome-lysosome system (ELS) and autophagy, ii.) ubiquitin-proteasome system (UPS) and iii.) stress proteins in the bio- and pathogenesis of conformational neurodegenerative diseases
research field in which current research is conducted biology
theoretical medicine
Publications
2018

Puska G, Lutz MI, Molnar K, Regelsberger G, Ricken G, Pirker W, Laszlo L, Kovacs GG: Lysosomal response in relation to α-synuclein pathology differs between Parkinson's disease and multiple system atrophy, NEUROBIOLOGY OF DISEASE 114: pp. 140-152.
type of document: Journal paper/Article
language: English
DOI 
2017

Ochalek A, Mihalik B, Avci HX, Chandrasekaran A, Teglasi A, Bock I, Giudice ML, Tancos Z, Molnar K, Laszlo L, Nielsen JE, Holst B, Freude K, Hyttel P, Kobolak J, Dinnyes A: Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation., ALZHEIMERS RESEARCH & THERAPY 9: (1) p. 90.
type of document: Journal paper/Article
language: English
URL 
2017

Chandrasekaran A, Avci HX, Ochalek A, Rosingh LN, Molnar K, Laszlo L, Bellak T, Teglasi A, Pesti K, Mike A, Phanthong P, Biro O, Hall V, Kitiyanant N, Krause KH, Kobolak J, Dinnyes A: Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells., STEM CELL RESEARCH 25: pp. 139-151.
type of document: Journal paper/Article
number of independent citations: 1
language: English
DOI 
2014

Kovacs GG, Breydo L, Green R, Kis V, Puska G, Lorincz P, Perju-Dumbrava L, Giera R, Pirker W, Lutz M, Lachmann I, Budka H, Uversky VN, Molnar K, Laszlo L: Intracellular processing of disease-associated alpha-synuclein in the human brain suggests prion-like cell-to-cell spread, NEUROBIOLOGY OF DISEASE 69: pp. 76-92.
type of document: Journal paper/Article
number of independent citations: 30
language: English
DOI 
2013

Toth E, Kulcsar PI, Fodor E, Ayaydin F, Kalmar L, Borsy AE, Laszlo L, Welker E: The highly conserved, N-terminal (RXXX)8 motif of mouse Shadoo mediates nuclear accumulation., BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833: (5) pp. 1199-1211.
type of document: Journal paper/Article
number of independent citations: 1
language: English
URL 
2002

Kovacs GG, Head MW, Hegyi I, Bunn TJ, Flicker H, Hainfellner JA, McCardle L, Laszlo L, Jarius C, Ironside JW, Budka H: Immunohistochemistry for the prion protein: Comparison of different monoclonal antibodies in human prion disease subtypes, BRAIN PATHOLOGY 12: (1) pp. 1-11.
type of document: Journal paper/Article
number of independent citations: 53
language: English
1997

Schatzl HM, Laszlo L, Holtzman DM, Tatzelt J, Dearmond SJ, Weiner RI, Mobley WC, Prusiner SB: A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis, JOURNAL OF VIROLOGY 71: (11) pp. 8821-8831.
type of document: Journal paper/Article
number of independent citations: 159
language: English
1995

ARNOLD JE, TIPLER C, LASZLO L, HOPE J, LANDON M, MAYER RJ: THE ABNORMAL ISOFORM OF THE PRION PROTEIN ACCUMULATES IN LATE-ENDOSOME-LIKE ORGANELLES IN SCRAPIE-INFECTED MOUSE-BRAIN, JOURNAL OF PATHOLOGY 176: (4) pp. 403-411.
type of document: Journal paper/Article
number of independent citations: 118
language: English
DOI 
1995

TARABOULOS A, SCOTT M, SEMENOV A, AVRAHAM D, LASZLO L, PRUSINER SB: CHOLESTEROL DEPLETION AND MODIFICATION OF COOH-TERMINAL TARGETING SEQUENCE OF THE PRION PROTEIN INHIBIT FORMATION OF THE SCRAPIE ISOFORM, JOURNAL OF CELL BIOLOGY 129: (1) pp. 121-132.
type of document: Journal paper/Article
number of independent citations: 381
language: English
DOI 
1992

LASZLO L, LOWE J, SELF T, KENWARD N, LANDON M, MCBRIDE T, FARQUHAR C, MCCONNELL I, BROWN J, HOPE J, MAYER RJ: LYSOSOMES AS KEY ORGANELLES IN THE PATHOGENESIS OF PRION ENCEPHALOPATHIES, JOURNAL OF PATHOLOGY 166: (4) pp. 333-341.
type of document: Journal paper/Article
number of independent citations: 114
language: English
DOI 
Number of independent citations to these publications:857 
Scientometric data
list of publications and citations
number of scientific publications that meet accreditation criteria:
60
number of scientific publications:
88
monographs and professional books:
0
monographs/books in which chapters/sections were contributed:
3 
scientific publications published abroad that meet the accreditation criteria:
57
publications not in Hungarian, published in Hungary, meeting the accreditation criteria:
3
number of independent citations to scientific publications and creative works:
2867

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )